DR. PAOLO ANGELINI, M.D.
Medical Practice at Fannin St, Houston, TX

5066282, Nov 19, 1991

May 4, 1989

7/347406

Bandula Wijay - Webster TX
Paolo Angelini - Houston TX

Leocor, Inc. - Houston TX

A61M 100

604152

The invention is a disposable, positive-displacement piston pump, having a polycarbonate body, a piston, an inlet valve, and an outlet valve. The outlet valve is connected to an exit chamber, which is separated from the exit valve by an elastomeric membrane. The elastomeric membrane encloses an accumulation chamber which is filled with a fluid such as air under atmospheric pressure. Pulsations in outlet pressure caused by stroking of the piston are dampened by the flexing action of the elastomeric membrane, compressing the fluid within the accumulator chamber. The throw out of the pump is pressure-dampened and is of sufficient pressure to flow through very low-profile angioplasty catheters having perfusion lumens extending therethrough. The combination of the pump with a very low-profile balloon angioplasty catheter allows access of the catheter to a constricted passage with the ability to pump a sufficient volume of blood through such a low-profile catheter during balloon inflations.

6997903, Feb 14, 2006

Feb 10, 2003

10/360803

Bandula Wijay - Friendswood TX, US
Paolo Angelini - Houston TX, US

A61M 5/00

604117

The present invention uses several innovative means in order to effectively puncture the intimal wall of blood vessels reliably and controllably. The total penetration of the needle is controlled by the height of the needle projecting from its base and the degree of penetration is controlled by the use of “cam” or similar means or mechanisms that moves the base containing the needles.

4884573, Dec 5, 1989

Mar 7, 1988

7/164870

Bandula Wijay - Friendswood TX
Paolo Angelini - Houston TX

Leocor, Inc. - Webster TX

A61M 2902

128344

A very low profile balloon catheter is disclosed that allows for an independently movable, steerable and removable guidewire. After removal of the guidewire, the balloon catheter retains adequately angiographic and hemodynamic characteristics. Such catheter construction allows for exchange of guidewires. A tracking mechanical device is included and provides excellent and easy advancement of the balloon catheter through severe obstructions.

4921483, May 1, 1990

Sep 23, 1987

7/100363

Bandula Wijay - Webster TX
Paolo Angelini - Houston TX

Leocor, Inc. - Webster TX

A61M 2902

604 96

An angioplasty catheter has an elongated body with at least one lumen extending therethrough. A tip, constructed of materials softer than the elongated body is attached to the distal end of the body. The tip segment has at least one lumen passing therethrough which is in alignment withthe lumen in the elongated body. A guide is adapted to pass through the aligned lumens. A balloon is connected to the distal segment of the elongated body over its outer periphery, thereby creating a balloon cavity therebetween. At least one additional lumen is provided in the elongated body in flow communication with the balloon cavity, for selective inflation and deflation thereof, with a contrast fluid.

5158540, Oct 27, 1992

May 22, 1990

7/527009

Bandula Wijay - Webster TX
Paolo Angelini - Houston TX

Leocor, Inc. - Houston TX

A61M 300

604 43

A low-profile angioplasty catheter is disclosed which is insertable through a guiding catheter. The angioplasty catheter has two balloons. The distal balloon dilates the stenosis. The proximal balloon is separately inflatable and selectively closes the annular passage between the angioplasty catheter and the guiding catheter. The angioplasty catheter has a central lumen with a series of openings allowing fluid communication from the central lumen into the annular passage proximally of the balloon which seals the annular passage. While the first balloon is inflated to dilate the stenosis, blood can be withdrawn from an arterial source through a lumen (or plurality thereof) in the guiding catheter and pumped into the annular passage between the angioplasty catheter and the guiding catheter. The blood then passes through the openings proximal to the proximal balloon into the central lumen of the PTCA catheter and flows beyond the distal tip of the angioplasty catheter to maintain circulation of the patient's blood at a point distal of the stenosis.