DR. OVIDIU PLATICA, M.D.
Osteopathic Medicine at 65 St, New York, NY
License number
New York 127957
Category
Osteopathic Medicine
Type
Hematology & Oncology
Address
Address
315 E 65Th St, New York, NY 10021
Phone
(212) 249-4843
(718) 630-3761 (Fax)
(718) 630-3761 (Fax)
Personal information
See more information about OVIDIU PLATICA at radaris.comName
Address
Phone
315 E 65Th St APT 11B, New York, NY 10065
3429 32Nd St, Astoria, NY 11106
6820 Selfridge St, Forest Hills, NY 11375
Professional information
Method Of Simultaneous Detection Of Base Changes (Sdbc) In Expressed Genes
US Patent:
6656686, Dec 2, 2003
Filed:
Mar 14, 2001
Appl. No.:
09/808504
Inventors:
Ovidiu Platica - New York NY 10021
International Classification:
C12Q 168
US Classification:
435 6, 536 231, 536 243, 935 76, 935 77, 935 78
Abstract:
This invention is directed to a method for detecting base changes in a nucleic acid of interest which comprise the following steps: (a) contacting the nucleic acid of interest with a suitable reference nucleic acid under suitable conditions that the nucleic acid of interest forms a heteroduplex with the reference nucleic acid; (b) contacting the heteroduplex with a combination of suitable nucleases so as to selectively cleave the heteroduplex if a base change(s) is present; (c) ligating a detectable probe to the cleaved heteroduplex; and (d) detecting the ligated probe under suitable conditions so as determine the location and the sequence of the base changes. The invention also includes kits for practicing the method. Also included are methods of identifying polymophisms associated with particular cancers.
Pituitary Differentiaton Factor And Methods Of Use Thereof
US Patent:
5888817, Mar 30, 1999
Filed:
Nov 25, 1997
Appl. No.:
8/977992
Inventors:
Micsunica Platica - New York NY
Ovidiu Platica - New York NY
James F. Holland - Scarsdale NY
Ovidiu Platica - New York NY
James F. Holland - Scarsdale NY
Assignee:
The Mount Sinai School of Medicine - New York NY
International Classification:
C12N 500, C12P 2102, C12P 2104
US Classification:
435377
Abstract:
The present invention is directed to pituitary differentiation factor (PDF), a pituitary factor that is capable of differentiating cells including breast cancer and prostatic cancer cells. Isolated nucleic acids encoding PDF and related vectors and host cells are also provided. Restoration of differentiating ability to malignantly transformed cells provides a modality of cancer therapy. The isolated and purified PDF of the invention is accordingly useful in the treatment of breast and prostatic cancer.
Pituitary Differentiation Factor And Methods Of Use Thereof
US Patent:
5795740, Aug 18, 1998
Filed:
Jul 9, 1997
Appl. No.:
8/890572
Inventors:
Micsunica Platica - New York NY
Ovidiu Platica - New York NY
James F. Holland - Scarsdale NY
Ovidiu Platica - New York NY
James F. Holland - Scarsdale NY
Assignee:
Mount Sinai School of Medicine - New York NY
International Classification:
C12N 1500, C07K 14435, C07H 2104
US Classification:
435 691
Abstract:
The present invention is directed to pituitary differentiation factor (PDF), a pituitary factor that is capable of differentiating cells including breast cancer and prostatic cancer cells. Isolated nucleic acids encoding PDF and related vectors and host cells are also provided. Restoration of differentiating ability to malignantly transformed cells provides a modality of cancer therapy. The isolated and purified PDF of the invention is accordingly useful in the treatment of breast and prostatic cancer.