Inventors:
Norman R. Farnsworth - Chicago IL
Geoffrey A. Cordell - Chicago IL
Masaru Ogura - Chicago IL
Assignee:
University of Illinois Foundation - Urbana IL
International Classification:
C07C 6974
Abstract:
An alcoholic extract of the plant Jacaranda caucana (Bignoniaceae) provides in vivo anti-tumor activity against the P-388 lymphocytic leukemia system. Fractionation of the extract by solvent extraction and chromatography afforded the active principle, a novel phytoquinoid derivative named jacaranone.