NICOLAE ISTRATE
Broker in Lexington, MA

License number
Massachusetts 9031711
Issued Date
Aug 6, 1999
Expiration Date
Mar 1, 2002
Type
Salesperson
Address
Address
Lexington, MA 02420

Professional information

Nicolae Istrate Photo 1

Methods For Treatment Of Human Immunodeficiency Virus Infection With Pseudomonas Phosphoaminolipid Extract

US Patent:
5853738, Dec 29, 1998
Filed:
Oct 30, 1995
Appl. No.:
8/550393
Inventors:
Nicolae Istrate - Lexington MA
Gita Muni - North Reading MA
Edgard Brauner - Brighton MA
Fazal Raheman - Burlington MA
Assignee:
Dynagen, Inc. - Cambridge MA
International Classification:
A61K 39108, A61K 3921, A61K 3902
US Classification:
4242601
Abstract:
The present invention is directed to a method of treating individuals infected with HIV or at risk of being infected with HIV. The method comprises the step of administering to an individual infected with HIV or at risk of being infected with HIV, an effective amount of a phosphoaminolipid extract derived from bacteria. The phosphoaminolipid extract exhibits an immunomodulating effect in humans, promoting a stabilization or improvement in immune system function.


Nicolae Istrate Photo 2

Methods For Prevention And/Or Treatment Of Neutropenia

US Patent:
5851534, Dec 22, 1998
Filed:
May 3, 1996
Appl. No.:
8/642425
Inventors:
Fazal Raheman - Burlington MA
Nicolae Istrate - Lexington MA
Gita Muni - North Reading MA
Edgard Brauner - Brighton MA
Assignee:
Dynagen, Inc. - Cambridge MA
International Classification:
A61K 39108
US Classification:
4242601
Abstract:
The present invention is directed to a method of treating individuals exhibiting neutropenia or at risk of neutropenia. The method comprises the step of administering to an individual exhibiting neutropenia or at risk of neutropenia, an effective amount of a colony modulating factor derived from bacteria. The colony factor modulator exhibits an immunomodulating effect in humans and promotes a stabilization or increase in neutrophil count.


Nicolae Istrate Photo 3

Methods For Prevention And/Or Treatment Of Thrombocytopenia

US Patent:
6183756, Feb 6, 2001
Filed:
May 1, 1997
Appl. No.:
8/846461
Inventors:
Nicolae Istrate - Lexington MA
Gita Muni - North Reading MA
Edgard Brauner - Brighton MA
Fazal Raheman - Burlington MA
Assignee:
Dynagen, Inc. - Cambridge MA
International Classification:
A61K 3910, A61K 3900, A61K 3938, A61K 3902
US Classification:
4242601
Abstract:
The present invention is directed to a method of treating subjects exhibiting thrombocytopenia or at risk of developing thrombocytopenia. The method includes the step of administering to the subject exhibiting thrombocytopenia or at risk of developing thrombocytopenia, an effective amount of a Pseudomonas solvent extract or active fraction thereof. The Pseudomonas solvent extract is administered in an amount effective to increase platelet levels in the subject.