Inventors:
Xiangping Qian - South San Francisco CA, US
Andrew I. McDonald - South San Francisco CA, US
Han-Jie Zhou - South San Francisco CA, US
Luke W. Ashcraft - South San Francisco CA, US
Bing Yao - South San Francisco CA, US
Hong Jiang - South San Francisco CA, US
Jennifer Kuo Chen Huang - South San Francisco CA, US
Jianchao Wang - South San Francisco CA, US
David J. Morgans - South San Francisco CA, US
Bradley P. Morgan - South San Francisco CA, US
Gustave Bergnes - South San Francisco CA, US
Dashyant Dhanak - Philadelphia PA, US
Steven D. Knight - Philadelphia PA, US
Nicholas D. Adams - Philadelphia PA, US
Cynthia A. Parrish - Philadelphia PA, US
Kevin Duffy - Philadelphia PA, US
Duke Fitch - Philadelphia PA, US
Rosanna Tedesco - Philadelphia PA, US
International Classification:
A61K 31/437, A61P 35/00
Abstract:
Compounds useful for treating cellular proliferative diseases and disorders by modulating the activity of one or more mitotic kinesins are disclosed.