Inventors:
Vlad Edward Gregor - Del Mar CA, US
Nelson Levy - Lake Forest IL, US
International Classification:
A61K 31/4545, A61K 31/5377, A61P 35/00, C12N 9/99, A61P 9/10, A61P 17/06, A61P 37/00, C07D 487/04, A61P 3/10
US Classification:
5142328, 546194, 514318, 546193, 544131, 435184
Abstract:
Provided are compounds of the formula (I):or a stereoisomer, tautomer, salt, hydrate or prodrug thereof that modulate tyrosine kinase activity, compositions comprising the compounds and methods of their use.