Inventors:
Donald P. Bottaro - Kensington MD, US
Megan Peach - Ashburn VA, US
Marc Nicklaus - Catonsville MD, US
Terrence Burke, JR. - Bethesda MD, US
Gagani Athauda - Southwest Ranches FL, US
Sarah Choyke - Rockville MD, US
Alessio Giubellino - Washington DC, US
Nelly Tan - Los Angeles CA, US
Assignee:
The Govt of the U.S.A., as rep.by the Sec.Dept of Hlth. and Human Svcs., Natl Institutes of Health - Rockville MD
International Classification:
A61K 31/5377, C07D 213/85, A61K 31/44, C07D 413/12, C07D 239/02, A61K 31/505, A61P 35/00
US Classification:
5142355, 546288, 514344, 544131, 544311, 514269
Abstract:
Derivatives and analogs of inhibitors of receptor tyrosine kinase c-Met, pharmaceutical compositions containing derivatives and analogs of c-Met inhibitors are provided. Methods of making derivatives and analogs of c-Met inhibitors and methods of use thereof are provided.