Neil Andrew Goldenberg
Physician Training at Sedalia St, Denver, CO

2008026, Oct 30, 2008

Sep 22, 2005

11/575853

Neil A. Goldenberg - Aurora CO, US
Marilyn J. Manco-Johnson - Greenwood Village CO, US
Linda Jacobson - Denver CO, US
William E. Hathaway - Denver CO, US

C12Q 1/56

435 13

The present disclosure concerns methods of analyzing both clot formation and fibrinolysis in a sample, preferably simultaneously. In certain embodiments, the methods may comprise adding a small amount of at least one activator of coagulation and at least one activator of fibrinolysis to a sample and analyzing the sample for kinetic parameters related to clot formation and fibrinolysis. In another embodiment, the methods may comprise analyzing a sample from a subject for clot formation and fibrinolysis and detecting or diagnosing a disease or condition and/or applying information obtained from analyzing clot formation and fibrinolysis to determine a treatment for a medical condition of the subject.

2013006, Mar 14, 2013

Nov 5, 2010

13/508341

Mindy Grunzke - Denver CO, US
Neil Goldenberg - Aurora CO, US
Marilyn J. Manco-Johnson - Greenwood Village CO, US
Linda Jacobson - Denver CO, US
William E. Hathaway - Denver CO, US

The Regents of the University of Colorado, a body corporate - Denver CO

C12Q 1/56, C12M 1/34, G01N 21/64

435 13, 4352871

Embodiments of the present invention report compositions and methods of analyzing thrombin and plasmin generation in a sample from a subject. In certain embodiments, the methods may comprise introducing at least one activator of coagulation and at least one activator of fibrinolysis to a sample and analyzing the sample for kinetic parameters related to thrombin and plasmin generation. In other embodiments, assays disclosed herein concern assessing net hemostatic balance of a subject for diagnostic and/or therapeutic applications.