Inventors:
Shadi Othman - Chicago IL, US
Nadia Halim - Chicago IL, US
Richard Magin - Western Springs IL, US
Jessy Mouannes - Elmwood Park IL, US
Neelima Vidula - Naperville IL, US
International Classification:
A61F 2/02, C12N 13/00
US Classification:
623023720, 435173100, 435173800
Abstract:
In an aspect the invention is a method of preparing a cell or tissue implant for insertion into a patient in need of treatment by obtaining a transplantable cell population, culturing the cell population in a culture media and exposing the cell population to a sonic or ultrasonic stimulation, wherein the stimulation provides a capability for an enhanced implant outcome parameter. The method provides enhanced autologous bone implant procedures by reducing the time required for a patient's own cells to sufficiently undergo osteogenesis, thereby reducing the waiting time for an autologous bone implant. The extent of osteogenesis is optionally monitored non-invasively by magnetic resonance spectroscopy.