Inventors:
Susan Lindquist - Chicago IL, US
Liming Li - Chicago IL, US
Jiyan Ma - Chicago IL, US
Jia-Jia Liu - Chicago IL, US
Neal Sondheimer - Chicago IL, US
Thomas Scheibel - Chicago IL, US
Assignee:
The University of Chicago - Chicago IL
International Classification:
A61K 38/00, C07K 14/00, C07K 16/00, C07K 17/00
US Classification:
530300, 530324, 530323, 530332, 530335, 930 20
Abstract:
The present invention provides novel polypeptides comprising a prion-aggregation domain and a second domain; novel polynucleotides encoding such polypeptides; host cells transformed or transfected with such polynucleotides; and methods of making and using the foregoing.