NAZLE B KUYLEN
Medical Practice at 109 St, Miami, FL

6692702, Feb 17, 2004

Jul 7, 2000

09/611847

Alexander Burshteyn - Hialeah FL
John W. Joubran - Miami FL
Nazle Kuylen - Miami FL
Frank J. Lucas - Boca Raton FL

Coulter International Corp. - Miami FL

G01N 134

422101, 422 8201, 422 8202, 436 63, 436178, 4353081, 2104161

A method for utilizing a filtration device for removing interferants from a sample containing cells in an automated apparatus is disclosed. The filtration device includes a microporous hollow fiber membrane having a plurality of pores sized to retain cells while allowing smaller diameter interferants to pass through the membrane. The apparatus also includes a means for of moving the sample from a sample container to and from the filtration device. The disclosed method utilizes a vacuum source to aspirate the sample into a lumen of the hollow fiber membrane so that the sample is retained in the lumen space until expelled into an analysis container or transported to an analyzer.

6692968, Feb 17, 2004

Sep 20, 2001

09/957234

Alexander Burshteyn - Hialeah FL
John W. Joubran - Escondido CA
Nazle Kuylen - Miami FL
Frank J. Lucas - Boca Raton FL
Carlos L. Aparicio - Miami FL
Michael L. Bell - Fullerton CA
Ravinder Gupta - Pembroke Pines FL
Maria Elena Insausti - Miami FL
Jack D. McNeal - Long Beach CA
Paul W. Price - Miami FL
Sandra Socarras - Miami FL

Coulter International Corp. - Miami FL

G01N 134

436 63, 210767, 422101, 4353081, 436178

A method for utilizing a filtration device for removing interferants from a test sample containing a mixture of a composition of interest and interferants in an automated apparatus is disclosed. The filtration device includes a microporous hollow fiber membrane having a plurality of pores sized to retain the composition of interest while allowing smaller diameter interferants to pass through the membrane.

5905031, May 18, 1999

Nov 1, 1996

8/742620

Nazle Kuylen - Miami FL
Harold R. Crews - Pembroke Pines FL
Gerald E. Jaffe - Pembroke Pines FL
Maria Barcelon - Ft. Lauderdale FL
Francis J. Lucas - Boca Raton FL
Nancy M. Garcia - Miami FL

Coulter International Corp. - Miami FL

C12Q1/02

435 29

The necessity to detect blast cells in a patient sample to determine a treatment regime for leukemia has long been desired. The present invention relates to a method and assay reagents for identification of blast cells in a fluid sample. The method further enables the determination of the lineage of the blast cells. The new method provides a determination of blast cells in less time than prior art methods.

2004013, Jul 8, 2004

Dec 19, 2003

10/741395

Alexander Burshteyn - Pembroke Pines FL, US
John Joubran - Escondido CA, US
Nazle Kuylen - Miami FL, US
Frank Lucas - Boca Raton FL, US
Carlos Aparicio - Miami FL, US
Michael Bell - Fullerton CA, US
Ravinder Gupta - Pembroke Pines FL, US
Maria Insausti - Miami FL, US
Jack McNeal - Long Beach CA, US
Paul Price - Miami FL, US
Sandra Socarras - Miami FL, US

Coulter International Corp. - Miami FL

G01N001/18

436/178000

A method for utilizing a filtration device for removing interferants from a test sample containing a mixture of a composition of interest and interferants in an automated apparatus is disclosed. The filtration device includes a microporous hollow fiber membrane having a plurality of pores sized to retain the composition of interest while allowing smaller diameter interferants to pass through the membrane.

2004013, Jul 8, 2004

Dec 19, 2003

10/741396

Alexander Burshteyn - Pembroke Pines FL, US
John Joubran - Escondido CA, US
Nazle Kuylen - Miami FL, US
Frank Lucas - Boca Raton FL, US

Coulter International Corp. - Miami FL

G01N033/48

436/063000

A method for utilizing a filtration device for removing interferants from a sample containing cells in an automated apparatus is disclosed. The filtration device includes a microporous hollow fiber membrane having a plurality of pores sized to retain cells while allowing smaller diameter interferants to pass through the membrane. The apparatus also includes a means for of moving the sample from a sample container to and from the filtration device. The disclosed method utilizes a vacuum source to aspirate the sample into a lumen of the hollow fiber membrane so that the sample is retained in the lumen space until expelled into an analysis container or transported to an analyzer.