Inventors:
Michael King - Rochester NY, US
Nichola Charles - Rochester NY, US
Jane Liesveld - Rochester NY, US
John Gentile - Spencerport NY, US
Kuldeepsinh Rana - Rochester NY, US
Nathan Clark - Rochester NY, US
Nipa Mody - West Henrietta NY, US
International Classification:
A61K 39/395, G01N 33/567, G01N 33/574
US Classification:
424140100, 435007210, 435007230
Abstract:
The present invention relates to methods and apparatuses for cell separation. In particular, the invention relates to separation of a particular cell type from a mixture of different cell types based on the differential rolling property of the particular cell type on a substrate coated with molecules that exhibits adhesive property with the particular cell type. This technology is adaptable for use in implantable shunts and devices for cell trafficking or tumor neutralization.