NANDITA DAS
Pharmacy in Carmel, IN
License number
New Jersey 28RI02550800
Issued Date
Nov 6, 1997
Expiration Date
Apr 30, 2019
Category
Pharmacy
Type
Pharmacist
Address
Address
Carmel, IN
Professional information
Dissolution Testing Of Solid Dosage Forms Intended To Be Administered In The Oral Cavity
US Patent:
2006028, Dec 28, 2006
Filed:
Jun 22, 2005
Appl. No.:
11/158903
Inventors:
Nandita Das - Carmel IN, US
Sudip Das - Carmel IN, US
Madhu Surapaneni - Wheeling IL, US
Sudip Das - Carmel IN, US
Madhu Surapaneni - Wheeling IL, US
International Classification:
G01N 33/15
US Classification:
073866000
Abstract:
The invention is a method and device for determining dissolution of a solid compound within the oral cavity. The device models dissolution within the oral cavity with a flow-through cell containing a solid compound and physiological amounts of simulated saliva. The device supplies and removes the simulated saliva at rates similar to production and loss of saliva within the oral cavity. The simulated saliva interaction with the solid compound mimics saliva interaction with a solid compound within the oral cavity. Dissolution of solid compound is determined from simulated saliva collected from the flow-through cell outflow.