Inventors:
Mukur Gupta - Morrisville NC, US
Brian Huber - Durham NC, US
Orest W. Blaschuk - Westmount, CA
Assignee:
ADHEREX TECHNOLOGIES, INC. - Ottawa
International Classification:
A61K 31/497, A61K 31/4196, C07D 401/04, A61K 31/4439, C07D 403/04, C07D 403/06, C07D 249/12, C07D 271/113, A61K 31/4245, C07D 271/06, C07D 233/58, A61K 31/4164, C07D 409/04, C12N 5/071, A61P 35/00, A61P 9/00, A61P 25/00, A61P 43/00, C07D 249/08
US Classification:
51425505, 5482694, 514383, 5482622, 5462724, 514340, 544405, 5482666, 5482632, 514384, 5482678, 548143, 514364, 548144, 548131, 5483435, 514396, 5482662, 435375
Abstract:
Compounds, particularly compounds having activity as modulators of cadherin-mediated cell adhesion having the following structure:or a pharmaceutically acceptable salt, stereoisomer or prodrug thereof,