MUKUR GUPTA
Pharmacy in Cary, NC
License number
Michigan 5302039292
Issued Date
Jul 28, 2009
Expiration Date
Jun 30, 2018
Category
Pharmacy
Type
Pharmacist
Address
Address
Cary, NC 27519
Professional information
Chemically Modified Cyclic Peptides Containing Cell Adhesion Recognition (Car) Sequences And Uses Therefor
US Patent:
2009013, May 21, 2009
Filed:
Jun 13, 2008
Appl. No.:
12/139270
Inventors:
Mukur Gupta - Morrisville NC, US
Brian Huber - Durham NC, US
William Paul Peters - Fernandina Beach FL, US
Brian Huber - Durham NC, US
William Paul Peters - Fernandina Beach FL, US
Assignee:
ADHEREX TECHNOLOGIES, INC. - Ottawa
International Classification:
A61K 38/16, C07K 14/00, A61P 35/00
US Classification:
514 11, 530317
Abstract:
Chemically modified cyclic peptides comprising cell adhesion recognition (CAR) sequences are provided having improved properties, such as improved stability. Also provided are methods of making and using same.
Compositions Comprising Topical Dpd Inhibitors And Methods Of Using Same In The Treatment Of Hand-Foot Syndrome
US Patent:
2009019, Aug 6, 2009
Filed:
Feb 6, 2009
Appl. No.:
12/367367
Inventors:
William Paul Peters - Fernandina Beach FL, US
Mukur Gupta - Morrisville NC, US
Mukur Gupta - Morrisville NC, US
Assignee:
ADHEREX TECHNOLOGIES INC. - Ottawa
International Classification:
A61K 9/12, A61K 31/513
US Classification:
424 45, 514274
Abstract:
Topical formulations comprising inhibitors of dihydropyrimidine dehydrogenase (DPD), thymidine phosphorylase (TP) and/or uridine phosphorylase (UP) enzyme inhibitors are provided for the treatment of hand-foot syndrome (HFS) in cancer patients undergoing treatment with 5-FU and 5-FU prodrugs.
Methods For Administering Dpd Inhibitors In Combination With 5-Fu And 5-Fu Prodrugs
US Patent:
2008025, Oct 16, 2008
Filed:
Feb 6, 2008
Appl. No.:
12/027064
Inventors:
William Paul Peters - Fernandina Beach FL, US
Mukur Gupta - Morrisville NC, US
Mukur Gupta - Morrisville NC, US
Assignee:
ADHEREX TECHNOLOGIES, INC. - Ottawa
International Classification:
A61K 31/505, A61P 17/00
US Classification:
514274
Abstract:
Methods for improved administration and dosing of DPD inhibitors in combination with 5-FU and/or 5-FU prodrugs are provided, comprising first administering to a patient in need thereof a DPD inhibitor that substantially eliminates activity of the enzyme and thereafter administering 5-FU or a 5-FU prodrug, wherein the level of 5-FU or 5-FU prodrug is in substantial excess of DPD inhibitor in the patient. Also provided are topical formulations comprising DPD, TP and/or UP inhibitors and methods of using same.
Small Molecule Modulators Of Cell Adhesion
US Patent:
2012002, Jan 26, 2012
Filed:
Feb 9, 2011
Appl. No.:
13/024025
Inventors:
Mukur Gupta - Morrisville NC, US
Brian Huber - Durham NC, US
Orest W. Blaschuk - Westmount, CA
Brian Huber - Durham NC, US
Orest W. Blaschuk - Westmount, CA
Assignee:
ADHEREX TECHNOLOGIES, INC. - Ottawa
International Classification:
A61K 31/497, A61K 31/4196, C07D 401/04, A61K 31/4439, C07D 403/04, C07D 403/06, C07D 249/12, C07D 271/113, A61K 31/4245, C07D 271/06, C07D 233/58, A61K 31/4164, C07D 409/04, C12N 5/071, A61P 35/00, A61P 9/00, A61P 25/00, A61P 43/00, C07D 249/08
US Classification:
51425505, 5482694, 514383, 5482622, 5462724, 514340, 544405, 5482666, 5482632, 514384, 5482678, 548143, 514364, 548144, 548131, 5483435, 514396, 5482662, 435375
Abstract:
Compounds, particularly compounds having activity as modulators of cadherin-mediated cell adhesion having the following structure:or a pharmaceutically acceptable salt, stereoisomer or prodrug thereof,
Small Molecule Modulators Of Cell Adhesion
US Patent:
2009029, Nov 26, 2009
Filed:
Mar 5, 2009
Appl. No.:
12/398649
Inventors:
Mukur Gupta - Morrisville NC, US
Brian Huber - Durham NC, US
Orest W. Blaschuk - Westmount, CA
Brian Huber - Durham NC, US
Orest W. Blaschuk - Westmount, CA
Assignee:
ADHEREX TECHNOLOGIES, INC. - Ottawa
International Classification:
A61K 31/4965, C07D 249/08, C07D 271/06, C07D 401/04, A61K 31/4196, A61K 31/4245, A61P 35/00
US Classification:
51425505, 5482622, 548132, 544405, 514384, 514364
Abstract:
Compounds, particularly compounds having activity as modulators of cadherin-mediated cell adhesion having the following structure:or a pharmaceutically acceptable salt, stereoisomer or prodrug thereof,