MORTON GERALD GLICKMAN
Medical Practice in New Haven, CT

5897533, Apr 27, 1999

Sep 2, 1997

8/922236

Morton G. Glickman - New Haven CT

Delcath Systems, Inc. - Stamford CT

A61M 500

604256

An arrangement for controlling the flow of blood between the annulus between a catheter and an elastomeric tube which encases it is provided. The arrangement also controls the ease of lateral movement of the catheter in relationship to the elastomeric tube. The arrangement includes a substantially rigid telescoping tube for supporting the elastomeric tube therewithin. The rigid telescoping tube further includes an inner tube having a pin disposed on the outer circumference thereof; and an outer tube having an opening therein forming a slot, and a plurality of substantially equally spaced stops; a first clamping arrangement for fixing one end of the elastomeric tube to the end of the outer tube furthest from the inner tube; and, a second clamping arrangement for fixing the other end of the elastomeric tube to the end of the inner tube furthest from the outer tube.

7022097, Apr 4, 2006

May 9, 2003

10/435579

Morton Glickman - New Haven CT, US

A61M 37/00, A61M 5/00, A01N 1/00, A61B 19/00

604 401, 604 8, 604 501, 128898, 435 11

A method for the in situ treatment of diseases and malignancies in a living host body. The method includes exposing a diseased or malignant gland of a host body to an effective amount of a therapeutic agent by infusing the therapeutic agent into blood flowing from the diseased or malignant gland that has been captured and contained in an isolated section associated with the gland. The contaminated blood from this isolated section is then evacuated from the host body, cleaned, detoxified and returned to the host body without exposing other glands, organs or tissue of the host body to the contaminated blood and without interrupting the normal flow of blood circulating through the host body.

2001004, Nov 15, 2001

Sep 2, 1997

08/922260

MORTON G. GLICKMAN - NEW HAVEN CT, US

A61M029/00

604/101010, 604/101030

The instant invention provides an apparatus, a kit and a method for treating a tumor in an extremity of a patient. The method first includes: providing a first catheter designed, sized and dimensioned for percutaneous insertion into the specific vein or portion of vein of the extremity receiving the blood from the tumor, including (a) a plastic tube having a cranial end and a caudal end, the plastic tube defining a main lumen for outflowing blood, two balloons, spaced apart about the plastic tube and bonded thereto for inflation thereabout, one being contiguous to the cranial end; wherein the balloons are sized and spaced on the plastic tube sufficient, that when inflated, they have sufficient size and spacing therebetween to substantially block the flow of blood in the vein and to substantially isolate outflow from the tumor to other portions of the vein; fenestrations in the plastic tube between the balloons to the main lumen; second and third lumina within the plastic tube; the second lumen connecting to one of the balloons; and, the third lumen connecting to the other of the balloons for effecting inflation or deflation of the balloons; the cranial end of the plastic tube being closed to substantially all inflow of blood. The method next includes: providing a second balloon catheter designed, sized and dimensioned for, in remaining part, isolating the area of the extremity by insertion into the specific artery or portion of the artery of the extremity feeding the blood to the tumor and for perfusing a chemotherapeutic agent into the area and tumor. The method next includes: perfusing the chemotherapeutic agent into the specific artery or portion of the artery through the second balloon catheter sufficient for effective therapeutic treatment of the tumor, withdrawing blood through the first catheter; and finally, recycling the blood from the withdrawing for reinfusion into the area and the tumor. The invention is applicable to any part of the body which can be described as an extremity, such as: an arm, a leg, a penis, a finger, a toe, a hand, a foot, a lower arm, or a lower leg.

5817046, Oct 6, 1998

Jul 14, 1997

8/891745

Morton G. Glickman - New Haven CT

Delcath Systems, Inc. - Stamford CT

A61M 3500

604 4

The instant invention provides a novel apparatus, kit and process for isolating a flow circuit within the pelvic cavity of a patient for perfusing a high concentration of a chemotherapeutic agent therethrough, without contaminating the blood circulating in the substantial remainder of the patient's blood circulatory system with the agent.

5893841, Apr 13, 1999

Aug 30, 1996

8/708046

Morton Glickman - New Haven CT

Delcath Systems, Inc. - Stamford CT

A61M 2900

604101

An improved balloon catheter with an inferior vena cava blood shunt or bypass is provided. Posterior and anterior ports in the wall of the catheter connect to a common lumen within the catheter, forming a shunt or bypass for blood flowing in the blood vessel. The blood shunt or bypass spans the blockage in the blood vessel generated by enlargement of the balloons of the balloon catheter. Bypass port closure apparatus is provided which is operated at the external end of the catheter. The bypass port closure device functions to open and close at least one of the ports of the bypass, effectively opening and closing the bypass.

6186146, Feb 13, 2001

Jan 13, 1997

8/782588

Morton Glickman - New Haven CT

A61B 1900

128898

An in situ treatment of an organ, such as a kidney, of a living body, having a disease or tumor. The method includes: subjecting a diseased or tumorous organ, such as a kidney, to an effective amount of a therapeutic agent, by infusing the agent via blood entering the organ, creating an isolated section in a major vein spanning the area where the tributary veins connect with the major vein, the major vein and tributary veins being directly associated with the organ; passing contaminated effluent blood from the tributary veins of the organ to the isolated section and capturing the effluent blood therein; and, evacuating the captured blood from the isolated section without exposing the contaminated effluent blood to other organs or tissues of the body and without interrupting the general circulation in the system of the body.

5919163, Jul 6, 1999

Jul 14, 1997

8/891744

Morton G. Glickman - New Haven CT

Delcath Systems, Inc. - Stamford CT

A61M 2900

604101

The instant invention provides a novel double balloon catheter which includes a first fixed balloon on the cranial end of the catheter; a second slidable balloon positioned around the catheter and spaced from the first fixed balloon; and, structure for enabling the second balloon to slide along the plastic tube between a first position defining a minimum distance between the first balloon and the second balloon, and a second position defining a maximum distance between the first balloon and the second balloon. The invention also contemplates a novel method of using the catheter.