Inventors:
Molly A. Hughes - Charlottesville VA, US
Robert M. Strieter - Charlottesville VA, US
Assignee:
UNIVERSITY OF VIRGINIA PATENT FOUNDATION - Charlottesville VA
International Classification:
A01N 37/46, A61K 39/07, A01N 25/34, A61K 38/19, A01P 1/00, A61P 31/04, A61K 9/00, C07K 14/32
US Classification:
424405, 424400, 4241901, 530350, 514 23, 514 24
Abstract:
The present invention provides proteins with antimicrobial activity, and methods for treating subjects by administering the proteins. In particular, the invention provides methods for treating and/or preventing microbial diseases and infections. The present invention further provides the target for these antimicrobial agents, as well as assays for identifying regulators of the target.