Mitchell V Palmer
Veterinary in Nevada, IA
License number
Utah 117962-2801
Issued Date
Jul 9, 1991
Expiration Date
Dec 31, 1992
Category
Veterinarian
Type
Veterinarian
Address
Address
Nevada, IA
Professional information
Diagnosis Of Pathogen Infections Through Analysis Of Nitrite Production By Antigen Stimulated Leukocytes
US Patent:
6673566, Jan 6, 2004
Filed:
Jan 10, 2002
Appl. No.:
10/044631
Inventors:
Wade R. Waters - Stratford IA
Mitchell V. Palmer - Nevada IA
Mitchell V. Palmer - Nevada IA
Assignee:
The United States of America as represented by the Secretary of Agriculture - Washington DC
International Classification:
C12N 500
US Classification:
435 27, 435 29, 435383
Abstract:
Peripheral blood mononuclear cells which have been isolated from an animal that is infected with a microbial pathogen produce nitric oxide in response to stimulation with antigens from that pathogen. Determination of nitric oxide production in cultures of peripheral blood mononuclear cells stimulated with a pathogens antigens may thus provide an indication of infection of the animal.
Recombinant Esat-6:Cfp-10 Fusion Protein Useful For Specific Diagnosis Of Tuberculosis
US Patent:
2006002, Feb 2, 2006
Filed:
Aug 2, 2004
Appl. No.:
10/909957
Inventors:
Wade Waters - Stratford IA, US
Mitchell Palmer - Nevada IA, US
Frank Minion - Ames IA, US
Mitchell Palmer - Nevada IA, US
Frank Minion - Ames IA, US
International Classification:
A61K 39/04, C07K 14/35
US Classification:
424248100, 530350000
Abstract:
The fusion protein rESAT-6:CFP-10 is useful for differentiating infection of an animal with from exposure of the animal to other species of , especially and subspecies (Map). Cells stimulated with the fusion protein are capable of eliciting a variety of in vivo and in vitro responses (e.g. hypersensitivity skin response, IFN-γ, nitric oxide, and TNF-α) indicative of infection. This invention will facilitate diagnosis of tuberculosis in cattle, reindeer and other susceptible animal species, thereby preventing unnecessary slaughter of uninfected animals suspected of having of the disease.