Inventors:
Adrian Ion Bot - Valencia CA, US
Zhiyong Qiu - San Gabriel CA, US
David C. Diamond - West Hills CA, US
Mihail Obrocea - Santa Clarita CA, US
Assignee:
MANNKIND CORPORATION - Valencia CA
International Classification:
A61K 39/00, A61P 37/04, A61P 35/00
Abstract:
The instant disclosure relates to methods for treating a cancer patient with an active immunotherapeutic, wherein the methods include assessing a patient's pre-existing immunoreactivity to at least one target antigen, choosing an immunotherapeutic regimen based on the level of pre-existing immunoreactivity, and administering an active immunotherapeutic according to the regimen.