MICHAL A ELOVITZ
Medical Practice in Penn Wynne, PA
License number
Pennsylvania MD417005
Category
Medicine
Type
Medical Physician and Surgeon
Address
Address
Penn Wynne, PA 19096
Professional information
Method Of Predicting Risk Of Pre-Term Birth
US Patent:
2012027, Oct 25, 2012
Filed:
Oct 28, 2010
Appl. No.:
13/504781
Inventors:
Michal A. Elovitz - Wynnewood PA, US
Assignee:
The Trustees of the University of Pennsylvania - Philadelphia PA
International Classification:
G01N 33/566, G01N 21/76, G01N 21/64, C12Q 1/68, C40B 30/04
US Classification:
506 9, 436501, 435 792, 435 612, 435 611
Abstract:
A method for diagnosing, or differentially diagnosing, an increased risk of pre-term birth (PTB) involves detecting or measuring increased expression of a biomarker Soluble E-cadherin (SE-CAD) in a biological sample from a mammalian subject, particularly in the urine, cervicovaginal fluid or blood. An increased level of expression of SE-CAD above the level of expression in the same sample of a healthy mammalian subject is an indication of a diagnosis of increased risk of PTB. Such diagnosis may further involve identify other clinical symptoms of PTB or PTL. Additionally the method may use additional biomarkers, such as fetal fibronectin.