Inventors:
Jennifer L. West - Houston TX, US
Christopher S. Chen - Princeton NJ, US
Jordan S. Miller - Philadelphia PA, US
Michael T. Yang - Philadelphia PA, US
International Classification:
A61K 9/70, A61K 35/00, A61K 38/00, B29C 47/00, A61K 35/12, B29D 7/01, C03C 25/68, B05D 5/00, A61K 9/00, A61K 31/7088
US Classification:
424443, 424400, 424 931, 514 11, 514 44 R, 424 937, 264 458, 216 7, 427243, 264465
Abstract:
Methods of fabricating a substantially interconnected model vasculature, as well as compositions formed from such methods are provided. In some embodiments, the methods may comprise forming a non-woven fiber network comprising a plurality of fibers and a void space; backfilling the void space of the fiber network; and removing the fibers to form a substantially interconnected vascular network.