Inventors:
Lawrence Solomon - Boca Raton FL, US
Michael Weber - New York NY, US
International Classification:
A61K 31/57, A61K 31/549
Abstract:
The invention relates to low dose combinations of a thiazide diuretic and a mineralocorticoid inhibitor and methods for the treatment of hypertension and related disorders. Methods and compositions for administering a thiazide diuretic, such as chlorthalidone, and an mineralocorticoid inhibitor such as spironolactone or eplerenone in a dose range of between 3 mg and 12 mg or eplerenone in a dose range of between 3 mg and 25 mg each,