Inventors:
Patrick S. Stayton - Seattle WA, US
Michael Nash - Seattle WA, US
Assignee:
University of Washington - Seattle WA
International Classification:
C12M 1/00, G01N 31/00, G01N 31/22, G01N 9/00
US Classification:
436149, 436 86, 436169, 436148, 436150, 436 94, 436 93, 436 91, 4351731, 4351739
Abstract:
System and method for capturing, concentrating, and detecting a diagnostic target in a liquid, comprising applying a magnetic field to a mixture comprising a co-aggregate in the liquid to provide a collected co-aggregate in the liquid, wherein the co-aggregate comprises a magnetic particle having a stimuli-responsive polymer attached thereto and a non-magnetic particle having a stimuli-responsive polymer and a diagnostic target attached thereto.