MICHAEL SAMOSZUK, M.D.
Medical Practice at Serna, Trabuco Canyon, CA
License number
California G44314
Category
Medical Practice
Type
Anatomic Pathology & Clinical Pathology
Address
Address
1 Serna, Trabuco Canyon, CA 92688
Phone
(949) 303-8011
Organization information
See more information about MICHAEL SAMOSZUK at bizstanding.comMichael Samoszuk M.D
1 Serna, Trabuco Canyon, CA 92688
Industry:
Medical Doctor's Office, Nonclassifiable Establishments
Medical Doctor:
Michael Samoszuk (Medical Doctor)
Professional information
Dr. Michael Samoszuk, Rancho Santa Margarita CA - MD (Doctor of Medicine)
Specialties:
Hematology, Hematopathology
Address:
1 Serna, Rancho Santa Margarita 92688
(949) 303-8011 (Phone)
(949) 303-8011 (Phone)
Certifications:
Anatomic & Clinical Pathology, 1983, Hematology & Pathology, 1999
Awards:
Healthgrades Honor Roll
Languages:
English
Education:
Medical School
Harvard Medical School
Graduated: 1979
Brigham and Womens Hospital
University Of California
University Of Southern California
Harvard Medical School
Graduated: 1979
Brigham and Womens Hospital
University Of California
University Of Southern California
Method Of Detecting Endometriosis
US Patent:
6540980, Apr 1, 2003
Filed:
Mar 31, 2000
Appl. No.:
09/541030
Inventors:
Rosalyn D. Blumenthal - Belleville NJ
David M. Goldenberg - Mendham NJ
Michael Samoszuk - Rancho Santa Margarita CA
David M. Goldenberg - Mendham NJ
Michael Samoszuk - Rancho Santa Margarita CA
Assignee:
Center for Molecular Medicine and Immunology - Belleville NJ
International Classification:
A61B 4900
US Classification:
424 934, 424 91, 424 111, 424 165, 424 93, 424 149
Abstract:
Kits for detecting and treating endometriosis are provided, which contain a targeting molecule comprising an eosinophil peroxidase-binding component. Methods of detecting and treating endometriosis using eosinophil peroxidase-specific targeting molecules are also provided Targeting molecules comprise an eosinophil peroxidase-binding component and an accessory component; the accessory component comprising an agent conferring detectability or a therapeutic effect.
Detection Of Clonal T-Cell Receptor- Gene Rearrangement By Pcr/Temporal Temperature Gradient Gel Electrophoresis (Ttge)
US Patent:
6720144, Apr 13, 2004
Filed:
Jun 21, 2001
Appl. No.:
09/886227
Inventors:
Michael Samoszuk - Rancho Santa Margarita CA
Dan Zhu - Irvine CA
Dan Zhu - Irvine CA
Assignee:
Quest Diagnostics - San Juan Capistrano CA
International Classification:
C12Q 168
US Classification:
435 6, 435 912, 435 9121, 435 915, 536 231, 536 243, 536 2431, 536 2433
Abstract:
The present invention provides methods and compositions for detecting and analyzing clonal T-cell receptor (TCR) gene rearrangement using temporal temperature gradient gel electrophoresis (TTGE), which employs a gradual and uniform increase in the temperature of a constant denaturing gel to resolve different DNA molecules based on base pair composition. The present invention also provides methods and compositions for providing appropriate DNA migration markers for TTGE analysis.
Methods For Measuring Microvascular Density In Tumors
US Patent:
6993175, Jan 31, 2006
Filed:
Sep 7, 2001
Appl. No.:
09/949292
Inventors:
Michael Samoszuk - Rancho Santa Margarita CA, US
Froilan Espinoza - Mission Viejo CA, US
Leonard Leonor - Dana Point CA, US
Froilan Espinoza - Mission Viejo CA, US
Leonard Leonor - Dana Point CA, US
Assignee:
Quest Diagnostics Investments Incorporated - Wilmington DE
International Classification:
G06K 9/00
US Classification:
382133, 128922
Abstract:
The present invention provides methods of determining the microvascular density of tumors. The methods generally comprise creating a digital image of a defined cross section of the tumor, determining the cross-sectional surface area of vascular tissue in the section of the tumor, determining the total cross sectional area of the section of the tumor, calculating the ratio of the cross sectional surface area of the tumor to the total cross sectional area of the section of the tumor, and thereby determining the microvascular density of the tumor. The digital image of the tumor may preferably be created using image processing software and the image may be displayed on a computer screen. The image may be digitally dissected by removing from the image all non-vascular tissue. This approach produces reproducible results that match the results generated by functional MRI assessments of blood perfusion of the tumors.
Detection Of Clonal T-Cell Receptor-Gamma Gene Rearrangement By Pcr/Temporal Temperature Gradient Gel Electrophoresis (Ttge)
US Patent:
2004024, Dec 9, 2004
Filed:
Apr 13, 2004
Appl. No.:
10/824187
Inventors:
Michael Samoszuk - Rancho Santa Margarita CA, US
Dan Zhu - Irvine CA, US
Dan Zhu - Irvine CA, US
Assignee:
Quest Diagnostics Investments Incorporated
International Classification:
C12Q001/68, C07H021/04
US Classification:
435/006000, 536/024300
Abstract:
The present invention provides methods and compositions for detecting and analyzing clonal T-cell receptor (TCR) gene rearrangement using temporal temperature gradient gel electrophoresis (TTGE), which employs a gradual and uniform increase in the temperature of a constant denaturing gel to resolve different DNA molecules based on base pair composition. The present invention also provides methods and compositions for providing appropriate DNA migration markers for TTGE analysis.
Assay For Bcr/Abl Gene Rearrangement
US Patent:
8367814, Feb 5, 2013
Filed:
Dec 9, 2009
Appl. No.:
12/634532
Inventors:
Richard W. Tseng - Mission Viejo CA, US
Michael K. Samoszuk - Rancho Santa Margarita CA, US
Michael K. Samoszuk - Rancho Santa Margarita CA, US
Assignee:
Quest Diagnostics Investments Incorporated - Wilmington DE
International Classification:
C07H 21/04, C12Q 1/68
US Classification:
536 243, 435 612
Abstract:
The present invention provides a simple high-throughput assay for detecting bcr/abl translocations. The method includes qualitative PCR methods for identifying the particular amplified translocation (e1a2 or b2a3/b3a2) and real time PCR for quantifying an amount of bcr/abl transcript (e1a2, b2a3 and b3a2). Quantitative measurement of bcr/abl transcript in accordance with the methods of the invention is useful for monitoring response to therapy.
Assay For Bcr/Abl Gene Rearrangement
US Patent:
7700279, Apr 20, 2010
Filed:
Dec 18, 2003
Appl. No.:
10/742616
Inventors:
Richard W. Tseng - Mission Viejo CA, US
Michael K. Samoszuk - Rancho Santa Margarita CA, US
Michael K. Samoszuk - Rancho Santa Margarita CA, US
Assignee:
Quest Diagnostics Investments Incorporated - Wilmington DE
International Classification:
C12Q 1/68, C12P 19/34, C07H 21/04
US Classification:
435 6, 435 912, 536 2431, 536 2432, 536 2433
Abstract:
The present invention provides a simple high-throughput assay for detecting bcr/abl translocations. The method includes qualitative PCR methods for identifying the particular amplified translocation (e1a2 or b2a3/b3a2) and real time PCR for quantifying an amount of bcr/abl transcript (e1a2, b2a3 and b3a2). Quantitative measurement of bcr/abl transcript in accordance with the methods of the invention is useful for monitoring response to therapy.
Bcr-Abl Gene Rearrangement Assay Method
US Patent:
2002019, Dec 19, 2002
Filed:
Dec 22, 2000
Appl. No.:
09/747165
Inventors:
Richard Tseng - , US
Michael Samoszuk - Rancho Santa Margarita CA, US
Michael Samoszuk - Rancho Santa Margarita CA, US
International Classification:
C12Q001/68, G06F019/00, G01N033/48, G01N033/50, C12P019/34
US Classification:
435/006000, 435/091200, 702/020000
Abstract:
Methods for assaying biological samples for bcr-abl translocation rearrangements and reporting the results of such assays which are useful in the diagnosis of CML and/or ALL are provided.