Inventors:
Michael B. Austin - San Diego CA, US
Joseph P. Noel - San Diego CA, US
Marianne E. Bowman - San Diego CA, US
International Classification:
C12N 9/00, C12N 15/00
Abstract:
Recombinant fusion proteins in which intermediates are covalently bound to the fusion proteins and transferred between domains of the fusion proteins are provided. The fusion proteins include proteins having type I polyketide or fatty acid synthase domains fused with type III polyketide synthase domains. Methods of making such recombinant fusion proteins and methods using such proteins to produce polyketide and other products are described.