MICHAEL ROBERT CANTRELL
Pilots at 38 St, Seattle, WA
License number
Washington A2810306
Issued Date
Mar 2017
Expiration Date
Mar 2018
Category
Airmen
Type
Authorized Aircraft Instructor
Address
Address
1112 N 38Th St, Seattle, WA 98056
Professional information
Dna Sequences Encoding Bovine Interleukin-2
US Patent:
4882282, Nov 21, 1989
Filed:
Jul 31, 1986
Appl. No.:
6/888994
Inventors:
Dirk M. Anderson - Seattle WA
Paul E. Baker - Bainbridge Island WA
Michael A. Cantrell - Seattle WA
Douglas P. Cerretti - Seattle WA
David J. Cosman - Seattle WA
Steven D. Gimpel - Seattle WA
Kenneth H. Grabstein - Seattle WA
Alf D. Larsen - Seattle WA
Kate N. McKereghan - Seattle WA
Paul E. Baker - Bainbridge Island WA
Michael A. Cantrell - Seattle WA
Douglas P. Cerretti - Seattle WA
David J. Cosman - Seattle WA
Steven D. Gimpel - Seattle WA
Kenneth H. Grabstein - Seattle WA
Alf D. Larsen - Seattle WA
Kate N. McKereghan - Seattle WA
Assignee:
Immunex Corporation - Seattle WA
International Classification:
C12N 100, C12N 1500, C12P 200, C12P 1734
US Classification:
4352523
Abstract:
A chemically-synthesized oligonucleotide composing a portion of the nucleotide sequence of the human IL-2 is employed as a probe to isolate the gene coding for human IL-2. The human IL-2 gene is selected from a cDNA library prepared from RNA produced by mitogen-stimulated Jurkat cells. Double-stranded cDNA is prepared from polyadenylated RNA extracted from bovine cells thought to produce interleukin-2. Such cDNA is inserted within a plasmid vector and the recombinant plasmid employed to transform hosts. Plasmid DNA, prepared from pools of the transformed hosts, is hybridized with a probe composed of a large portion of the coding sequence of the human IL-2 gene. Pools of host cells that provide signal to the human cDNA probe are identified, subdivided, and rescreened until a single positive colony is identified. Bovine plasmid cDNA is prepared from this colony, and the bIL-2 gene is sequenced. The plasmid DNA is employed to express recombinant bovine IL-2 in yeast and bacterial expression systems, with the expressed bovine IL-2 purified to homogeneity by one or more reverse phase high-performance liquid chromatography procedures.
Process For Preparing Bovine Interleukin-2
US Patent:
5006465, Apr 9, 1991
Filed:
Aug 11, 1989
Appl. No.:
7/392811
Inventors:
Dirk M. Anderson - Seattle WA
Paul E. Baker - Bainbridge Island WA
Michael A. Cantrell - Seattle WA
Douglas P. Cerretti - Seattle WA
David J. Cosman - Seattle WA
Steven D. Gimpel - Seattle WA
Kenneth H. Grabstein - Seattle WA
Alf D. Larsen - Seattle WA
Kate N. McKereghan - Seattle WA
Paul E. Baker - Bainbridge Island WA
Michael A. Cantrell - Seattle WA
Douglas P. Cerretti - Seattle WA
David J. Cosman - Seattle WA
Steven D. Gimpel - Seattle WA
Kenneth H. Grabstein - Seattle WA
Alf D. Larsen - Seattle WA
Kate N. McKereghan - Seattle WA
International Classification:
C12P 2106, C12P 1934, C12N 1500, C12N 120, C12N 114, C12N 118, C12N 1500, C07H 1512, C07K 300
US Classification:
435 6952
Abstract:
A process for preparing bovine interleukin-2 (bIL-2) by culturing a microbial host transformed by a vector containing a DNA sequence encoding bIL-2 under conditions suitable for the expression of bIL-2 and recovering bIL-2.
Production Of Phytate Degrading Enzymes In Trichoderma
US Patent:
5780292, Jul 14, 1998
Filed:
Jul 31, 1992
Appl. No.:
7/923724
Inventors:
Helena K. M. Nevalainen - Espoo, FI
Marja T. Paloheimo - Helsinki, FI
Aria S. K. Miettinen-Oinonen - Masala, FI
Tuula K. Torkkeli - Helsinki, FI
Michael Cantrell - Seattle WA
Cristopher S. Piddington - Seattle WA
John A. Rambosek - Seattle WA
Marja K. Turunen - Helsinki, FI
Richard B. Fagerstrom - Espoo, FI
Marja T. Paloheimo - Helsinki, FI
Aria S. K. Miettinen-Oinonen - Masala, FI
Tuula K. Torkkeli - Helsinki, FI
Michael Cantrell - Seattle WA
Cristopher S. Piddington - Seattle WA
John A. Rambosek - Seattle WA
Marja K. Turunen - Helsinki, FI
Richard B. Fagerstrom - Espoo, FI
Assignee:
Alko Group Ltd. - Helsinki
International Classification:
C12N 114, C12N 115, C12N 916, A23K 100
US Classification:
4352568
Abstract:
A highly efficient overexpression system for phytase and pH 2. 5 acid phosphatase in Trichoderma is described. This system results in enzyme compositions that are especially useful in the animal feed industry.