Michael Rex Lappin
Veterinary in Fort Collins, CO

License number
Colorado 3723
Issued Date
Jun 9, 1981
Renew Date
Jul 21, 2015
Expiration Date
Oct 31, 2016
Type
Veterinarian
Address
Address 2
625 Gait Crk, Fort Collins, CO 80524
Fort Collins, CO

Professional information

Michael Lappin Photo 1

Professor At Colorado State University

Position:
Professor at Colorado State University
Location:
Fort Collins, Colorado Area
Industry:
Veterinary
Work:
Colorado State University - Professor


Michael Lappin Photo 2

Use Of Recombinant Antigens To Determine The Immune Status Of An Animal

US Patent:
2004005, Mar 25, 2004
Filed:
Sep 25, 2003
Appl. No.:
10/670695
Inventors:
Wayne Jensen - Wellington CO, US
Michael Lappin - Fort Collins CO, US
David Rosen - Portage MI, US
Janet Andrews - Fort Collins CO, US
International Classification:
C12Q001/70, G01N033/554, G01N033/569
US Classification:
435/005000, 435/007320
Abstract:
The present invention includes a method to determine the immune status of an animal that includes the steps of (a) contacting a biological specimen of the animal with a recombinant infectious agent antigen that is specific for detecting an antibody selective for that infectious agent, under conditions suitable for formation of a complex between the recombinant antigen and the antibody and (b) detecting the presence or absence of the complex, wherein presence or absence of a complex is indicative of the immune status of the animal. Preferably such a method indicates whether the animal should be vaccinated. The present invention also includes an assay comprising (a) a recombinant infectious agent antigen that is specific for detecting an antibody selective for that infectious agent; and (b) a means to detect an antibody that selectively binds to the recombinant antigen. Also included in the present invention are recombinant antigens and nucleic acid molecules encoding such antigens as well as methods to produce and use such nucleic acid molecule and recombinant antigens.


Michael Lappin Photo 3

Use Of Recombinant Antigens To Determine The Immune Status Of An Animal

US Patent:
2008028, Nov 20, 2008
Filed:
May 29, 2008
Appl. No.:
12/128862
Inventors:
Wayne A. Jensen - Wellington CO, US
Michael R. Lappin - Fort Collins CO, US
David K. Rosen - Portage MI, US
Janet S. Andrews - Fort Collins CO, US
International Classification:
A61K 39/00, A61P 37/00
US Classification:
4241871, 4241841, 4242041, 4242131, 4242311, 4242241, 4242331, 4241861, 4242071
Abstract:
The present invention includes a method to determine the immune status of an animal that includes the steps of (a) contacting a biological specimen of the animal with a recombinant infectious agent antigen that is specific for detecting an antibody selective for that infectious agent, under conditions suitable for formation of a complex between the recombinant antigen and the antibody and (b) detecting the presence or absence of the complex, wherein presence or absence of a complex is indicative of the immune status of the animal. Preferably such a method indicates whether the animal should be vaccinated. The present invention also includes an assay comprising (a) a recombinant infectious agent antigen that is specific for detecting an antibody selective for that infectious agent; and (b) a means to detect an antibody that selectively binds to the recombinant antigen. Also included in the present invention are recombinant antigens and nucleic acid molecules encoding such antigens as well as methods to produce and use such nucleic acid molecule and recombinant antigens.