MICHAEL R ZILE, MD
Osteopathic Medicine at Ashley Ave, Charleston, SC
License number
South Carolina 14063
Category
Osteopathic Medicine
Type
Cardiovascular Disease
Address
Address
2
171 Ashley Ave, Charleston, SC 29425
PO Box 751461, Charlotte, NC 28275
PO Box 751461, Charlotte, NC 28275
Phone
(843) 792-1414
(843) 792-6200
(843) 792-6200
Personal information
See more information about MICHAEL R ZILE at radaris.comName
Address
Phone
951 Paul Revere Dr, Charleston, SC 29412
20 Ocean Green Dr, Johns Island, SC 29455
951 Paul Revere Dr, James Island, SC 29412
Organization information
See more information about MICHAEL R ZILE at bizstanding.comDigestive Disease Center - Michael R Zile MD
25 Courtenay Dr #7, Charleston, SC 29425
Categories:
Cardiology Physicians & Surgeons
Phone:
(843) 792-3355 (Phone)
Professional information
Detecting And Monitoring Left Ventricular Hypertrophy And Congestive Heart Failure By Profiling Biomarkers
US Patent:
2012001, Jan 12, 2012
Filed:
Nov 4, 2009
Appl. No.:
13/128200
Inventors:
Francis G. Spinale - Chareleston SC, US
Michael R. Zile - Charleston SC, US
Robert E. Stroud - Mt. Pleasant SC, US
Michael R. Zile - Charleston SC, US
Robert E. Stroud - Mt. Pleasant SC, US
Assignee:
MUSC Foundation for Research Development - Charleston SC
International Classification:
C40B 30/04, G01N 33/566, G01N 33/573, C12Q 1/37
US Classification:
506 9, 435 23, 435 792, 435 74, 436501
Abstract:
Disclosed herein are methods of detecting, monitoring, and predicting left ventricular hypertrophy, congestive heart failure and related conditions by profiling biomarkers.
Michael Robert Zile, Charleston SC
Specialties:
Internal Medicine, Cardiovascular Disease, Cardiology
Work:
Medical University of South Carolina
171 Ashley Ave, Charleston, SC 29425 Medical University of South Carolina
25 Courtenay Dr, Charleston, SC 29425
171 Ashley Ave, Charleston, SC 29425 Medical University of South Carolina
25 Courtenay Dr, Charleston, SC 29425
Education:
Rush Medical College (1977)
Assessing Left Ventricular Remodeling Via Temporal Detection And Measurement Of Microrna In Body Fluids
US Patent:
8592151, Nov 26, 2013
Filed:
Nov 11, 2010
Appl. No.:
12/944670
Inventors:
Francis G. Spinale - Charleston SC, US
Michael R. Zile - Charleston SC, US
Robert E. Stroud - Mt. Pleasant SC, US
Michael R. Zile - Charleston SC, US
Robert E. Stroud - Mt. Pleasant SC, US
Assignee:
MUSC Foundation for Research Development - Charleston SC
International Classification:
C12Q 1/68
US Classification:
435 61, 435 611
Abstract:
Disclosed are methods and materials for assessing cardiac failure, cardiac hypertrophy, and left ventricular remodeling using microRNA levels. The level of microRNAs can be measured in a body fluid, such as plasma and serum.
Detecting Diastolic Heart Failure By Protease And Protease Inhibitor Plasma Profiling
US Patent:
2009022, Sep 3, 2009
Filed:
Apr 24, 2007
Appl. No.:
12/299999
Inventors:
Francis G. Spinale - Charleston SC, US
Robert E. Stroud - Mt. Pleasant SC, US
Michael R. Zile - Charleston SC, US
Robert E. Stroud - Mt. Pleasant SC, US
Michael R. Zile - Charleston SC, US
International Classification:
C12Q 1/37
US Classification:
435 23
Abstract:
Disclosed herein are methods of detecting and predicting diastolic heart failure and predicting congestive heart failure comprise protease and protease inhibitor profiling.
Predicting Heart Failure Following Myocardial Infarction By Protease And Protease Inhibitor Profiling
US Patent:
2010001, Jan 21, 2010
Filed:
Jul 11, 2007
Appl. No.:
12/307985
Inventors:
Francis G. Spinale - Charleston SC, US
Robert E. Stroud - Mt. Pleasant SC, US
Michael R. Zile - Charleston SC, US
Robert E. Stroud - Mt. Pleasant SC, US
Michael R. Zile - Charleston SC, US
Assignee:
MUSC Foundation for Research Development - Charleston SC
International Classification:
C12Q 1/37
US Classification:
435 23
Abstract:
Disclosed herein are methods of detecting or predicting diastolic heart failure in a subject, comprising identifying a profile of matrix metalloproteinases (MMPs) and tissue inhibitors of matrix metalloproteinases (TIMPs) from a body fluid of the subject that is associated herein with the existence of likely development of left ventricular dilation (LVD).
Assessing Cardiac Disease Via Detection And Measurement Of Microrna
US Patent:
2013028, Oct 31, 2013
Filed:
Nov 11, 2011
Appl. No.:
13/884861
Inventors:
Francis G. Spinale - Blythewood SC, US
Michael R. Zile - Charleston SC, US
Robert E. Stoud - Mount Pleasant SC, US
John S. Ikonomidis - Mount Pleasant SC, US
Jeffrey A. Jones - Charleston SC, US
Michael R. Zile - Charleston SC, US
Robert E. Stoud - Mount Pleasant SC, US
John S. Ikonomidis - Mount Pleasant SC, US
Jeffrey A. Jones - Charleston SC, US
Assignee:
Medical University of South Carolina - Charleston SC
International Classification:
C12Q 1/68
US Classification:
514789, 435 612, 506 9
Abstract:
Disclosed are methods and materials for assessing cardiac disease, including cardiac failure, cardiac hypertrophy, thoracic aortic aneurysm, left ventricular remodeling using microRNA levels. The level of microRNAs can be measured in a body fluid, such as plasma and serum, or in cardiac tissue.