Inventors:
Brian M. Beyer - Matawan NJ, US
Thomas Hesson - Burlington MA, US
Hung V. Le - Rockaway NJ, US
Andrew J. Prongay - Billerica MA, US
Krishna Kalghatgi - Westborough MA, US
Jennifer Joanne Gesell - Allentown NJ, US
Richard N. Ingram - Scotch Plains NJ, US
Michael R. Ziebell - Arlington MA, US
Assignee:
Schering Corporation - Kenilworth NJ
International Classification:
C12Q 1/37
Abstract:
The present invention provides methods for identifying modulators of PCSK9, for example, using a variety of assay formats. Inhibitors of PCSK9 can be used for example, to treat diseases such as hyperlipidemia and related disorders.