MICHAEL P ROBERTS
Physician in Gainesville, FL
License number
Florida 9115
Issued Date
May 20, 2005
Effective Date
Aug 17, 2011
Expiration Date
Jul 1, 2009
Category
Health Care
Type
Registration for Resident/HSE Physician
Address
Address
PO Box 100005, Gainesville, FL 32610
Professional information
Connective-Tissue-Based Or Dermal-Tissue-Based Grafts/Implants
US Patent:
8394141, Mar 12, 2013
Filed:
Sep 9, 2010
Appl. No.:
12/807599
Inventors:
C. Randal Mills - Tioga FL, US
John R. Bianchi - Gainesville FL, US
Michael R. Roberts - Gainesville FL, US
David T. Cheung - Arcadia CA, US
Chandrasekaran Nataraj - Gainesville FL, US
John W. Howell - Gainesville FL, US
John R. Bianchi - Gainesville FL, US
Michael R. Roberts - Gainesville FL, US
David T. Cheung - Arcadia CA, US
Chandrasekaran Nataraj - Gainesville FL, US
John W. Howell - Gainesville FL, US
Assignee:
RTI Biologics, Inc. - Dover DE
International Classification:
A61F 2/08, A61F 2/10, A61K 38/18
US Classification:
623 1311, 623 1317, 623 132, 623 1512, 424423, 514 76, 514 94
Abstract:
The present invention is directed to a composition comprising a matrix suitable for implantation in humans, comprising defatted, shredded, allogeneic human muscle tissue that has been combined with an aqueous carrier and dried in a predetermined shape. Also disclosed is a tissue graft or implant comprising a matrix suitable for implantation in humans, comprising defatted, shredded, allogeneic human muscle tissue that has been combined with an aqueous carrier and dried in a predetermined shape. The composition and/or tissue graft or implant of the invention is usable in combination with seeded cells, a tissue growth factor, and/or a chemotactic gent to attract a desired cell.
Muscle-Based Grafts/Implants
US Patent:
7131994, Nov 7, 2006
Filed:
Mar 5, 2004
Appl. No.:
10/793976
Inventors:
C. Randal Mills - Tioga FL, US
John R. Bianchi - Gainesville FL, US
Michael R. Roberts - Gainesville FL, US
David T. Cheung - Arcadia CA, US
Chandrasekaran Nataraj - Gainesville FL, US
John R. Bianchi - Gainesville FL, US
Michael R. Roberts - Gainesville FL, US
David T. Cheung - Arcadia CA, US
Chandrasekaran Nataraj - Gainesville FL, US
Assignee:
Regeneration Technologies, Inc. - Alachua FL
International Classification:
A61F 2/08, A61K 35/34, A61K 38/17
US Classification:
623 1413, 424423, 424548, 514 12
Abstract:
The present invention is directed to a composition comprising a matrix suitable for implantation in humans, comprising defatted, shredded, allogeneic human muscle tissue that has been combined with an aqueous carrier and dried in a predetermined shape. Also disclosed is a tissue graft or implant comprising a matrix suitable for implantation in humans, comprising defatted, shredded, allogeneic human muscle tissue that has been combined with an aqueous carrier and dried in a predetermined shape. The composition and/or tissue graft or implant of the invention is usable in combination with seeded cells, a tissue growth factor, and/or a chemotactic agent to attract a desired cell.
Muscle-Based Grafts/Implants
US Patent:
2006025, Nov 9, 2006
Filed:
Jul 3, 2006
Appl. No.:
11/480711
Inventors:
C. Mills - Tioga FL, US
John Bianchi - Gainesville FL, US
Michael Roberts - Gainesville FL, US
David Cheung - Arcadia CA, US
Chandrasekaran Nataraj - Gainesville FL, US
John Howell - Gainesville FL, US
John Bianchi - Gainesville FL, US
Michael Roberts - Gainesville FL, US
David Cheung - Arcadia CA, US
Chandrasekaran Nataraj - Gainesville FL, US
John Howell - Gainesville FL, US
International Classification:
A61K 38/17, A61K 35/12, A61F 2/06
US Classification:
424093700, 514012000, 623001110
Abstract:
The present invention is directed to a composition comprising a matrix suitable for implantation in humans, comprising defatted, shredded, allogeneic human muscle tissue that has been combined with an aqueous carrier and dried in a predetermined shape. Also disclosed is a tissue graft or implant comprising a matrix suitable for implantation in humans, comprising defatted, shredded, allogeneic human muscle tissue that has been combined with an aqueous carrier and dried in a predetermined shape. The composition and/or tissue graft or implant of the invention is usable in combination with seeded cells, a tissue growth factor, and/or a chemotactic agent to attract a desired cell.
Muscle-Based Grafts/Implants
US Patent:
2013014, Jun 13, 2013
Filed:
Feb 7, 2013
Appl. No.:
13/815184
Inventors:
C. Randal Mills - Tioga FL, US
John R. Bianchi - Gainesville FL, US
Michael R. Roberts - Gainesville FL, US
David T. Cheung - Arcadia CA, US
Chandrasekaran Nataraj - Gainesville FL, US
John W. Howell - Gainesville FL, US
John R. Bianchi - Gainesville FL, US
Michael R. Roberts - Gainesville FL, US
David T. Cheung - Arcadia CA, US
Chandrasekaran Nataraj - Gainesville FL, US
John W. Howell - Gainesville FL, US
Assignee:
RTI BIOLOGICS, INC. - Dover DE
International Classification:
A61L 27/36, A61L 27/56
US Classification:
424400, 514772, 424549, 424 937
Abstract:
The present invention is directed to a composition comprising a matrix suitable for implantation in humans, comprising defatted, shredded, allogeneic human muscle tissue that has been combined with an aqueous carrier and dried in a predetermined shape. Also disclosed is a tissue graft or implant comprising a matrix suitable for implantation in humans, comprising defatted, shredded, allogeneic human muscle tissue that has been combined with an aqueous carrier and dried in a predetermined shape. The composition and/or tissue graft or implant of the invention is usable in combination with seeded cells, a tissue growth factor, and/or a chemotactic agent to attract a desired cell.
Muscle-Based Grafts/Implants
US Patent:
7883541, Feb 8, 2011
Filed:
Dec 3, 2007
Appl. No.:
11/949687
Inventors:
C. Randal Mills - Tioga FL, US
John R. Bianchi - Gainesville FL, US
Michael R. Roberts - Gainesville FL, US
David T. Cheung - Arcadia CA, US
Chandrasekaran Nataraj - Gainesville FL, US
John R. Bianchi - Gainesville FL, US
Michael R. Roberts - Gainesville FL, US
David T. Cheung - Arcadia CA, US
Chandrasekaran Nataraj - Gainesville FL, US
Assignee:
RTI Biologics, Inc. - Alachua FL
International Classification:
A61F 2/08, A61K 35/34, A61K 38/17, A61K 38/18
US Classification:
623 1413, 424423, 424548, 514 12, 530399
Abstract:
The present invention is directed to a composition comprising a matrix suitable for implantation in humans, comprising defatted, shredded, allogeneic human muscle tissue that has been combined with an aqueous carrier and dried in a predetermined shape. Also disclosed is a tissue graft or implant comprising a matrix suitable for implantation in humans, comprising defatted, shredded, allogeneic human muscle tissue that has been combined with an aqueous carrier and dried in a predetermined shape. The composition and/or tissue graft or implant of the invention is usable in combination with seeded cells, a tissue growth factor, and/or a chemotactic agent to attract a desired cell.
Matrix Composition For Human Grafts/Implants
US Patent:
7001430, Feb 21, 2006
Filed:
Jan 9, 2004
Appl. No.:
10/754310
Inventors:
C. Randal Mills - Tioga FL, US
John R. Bianchi - Gainesville FL, US
Michael R. Roberts - Gainesville FL, US
David T. Cheung - Arcadia CA, US
Chandrasekaran Nataraj - Gainesville FL, US
John R. Bianchi - Gainesville FL, US
Michael R. Roberts - Gainesville FL, US
David T. Cheung - Arcadia CA, US
Chandrasekaran Nataraj - Gainesville FL, US
Assignee:
Regeneration Technologies, Inc. - Alachua FL
International Classification:
A61F 2/08, A61F 2/02, A61K 38/17, A61K 35/34
US Classification:
623 1413, 424423, 424424, 424548, 514 12
Abstract:
The present invention is directed to an intermediate composition for producing a muscle tissue matrix suitable for implantation in humans, comprising shredded, allogeneic human muscle tissue that has been combined with an aqueous carrier, preferably a biocompatible acid solution, to form a muscle tissue slurry having a viscosity within the range of 1 centistoke to 20,000 centistokes measured at 25° C. In another aspect, the present invention is directed to a tissue implant comprising a human muscle tissue matrix.