Inventors:
Bruce Auerbach - Ann Arbor MI, US
Michael Ryan - Ann Arbor MI, US
Karen Hitchcock - Pompton Plains NJ, US
International Classification:
A61K031/47, A61K031/19, A61K031/455
US Classification:
514/310000, 514/355000, 514/574000
Abstract:
The invention is a pharmaceutical composition comprising a carboxyalkylether of the formula (I) wherein R, R, R, and Rinclude alkyl, alkenyl, and alkynyl, m and n are integers from 2 to 9, Yand Yinclude COOH, CHO, tetrazole, COORwhere Ris alkyl, alkenyl, or alkynyl, or a pharmaceutically acceptable salt therof, and an antihypertensive agent, said composition being useful for treating vascular diseases. The invention includes a method of treating hypertension comprising
administering a carboxyalkylether.