MICHAEL J. MILLER, MD
Radiology at Sunset Blvd, Los Angeles, CA

2013033, Dec 12, 2013

Feb 27, 2013

13/778433

Medtronic Minimed, Inc. - , US
Michael E. Miller - Culver City CA, US
Rajiv Shah - Rancho Palos Verdes CA, US

A61B 5/145, A61B 5/00, A61B 5/1473

600347

A diagnostic Electrochemical Impedance Spectroscopy (EIS) procedure is applied to measure values of impedance-related parameters for one or more sensing electrodes. The parameters may include real impedance, imaginary impedance, impedance magnitude, and/or phase angle. The measured values of the impedance-related parameters are then used in performing sensor diagnostics, calculating a highly-reliable fused sensor glucose value based on signals from a plurality of redundant sensing electrodes, calibrating sensors, detecting interferents within close proximity of one or more sensing electrodes, and testing surface area characteristics of electroplated electrodes. Advantageously, impedance-related parameters can be defined that are substantially glucose-independent over specific ranges of frequencies. An Application Specific Integrated Circuit (ASIC) enables implementation of the EIS-based diagnostics, fusion algorithms, and other processes based on measurement of EIS-based parameters.

2003006, Mar 27, 2003

Dec 26, 2001

10/033173

Timothy Starkweather - Simi Valley CA, US
Ronald Lebel - Sherman Oaks CA, US
Rajiv Shah - Rancho Palos Verdes CA, US
Michael Miller - Los Angeles CA, US

A61M031/00

604/066000, 604/500000

A system and method for providing closed loop infusion formulation delivery which accurately calculates a delivery amount based on a sensed biological state by adjusting an algorithm's programmable control parameters. The algorithm calculates a delivery amount having proportional, derivative, and basal rate components. The control parameters may be adjusted in real time to compensate for changes in a sensed biological state that may result from daily events. Safety limits on the delivery amount may be included in the algorithm. The algorithm may be executed by a computing element within a process controller for controlling closed loop infusion formulation delivery. The biological state is sensed by a sensing device which provides a signal to the controller. The controller calculates an infusion formulation delivery amount based on the signal and sends commands to an infusion formulation delivery device which delivers an amount of infusion formulation determined by the commands.

2003022, Nov 27, 2003

Feb 12, 2003

10/365279

Bahar Reghabi - Marina Del Rey CA, US
Rajiv Shah - Rancho Palos Verdes CA, US
Eunjoo Jin - Los Angeles CA, US
Rebecca Gottlieb - Culver City CA, US
Michael Miller - Culver City CA, US
Nannette Van Antwerp - Valencia CA, US
Bradley Enegren - Moorpark CA, US
William Van Antwerp - Valencia CA, US
John Mastrototaro - Los Angeles CA, US

MEDTRONIC MINIMED, INC.

A61B005/00

600/365000

A reusable analyte sensor site for use with a replaceable analyte sensor for determining a level of an analyte includes a site housing material and a resealable insertion site coupled to one end of the site housing material. Preferably, the site housing material is formed to have an interior cavity with an opening. The site housing material is selected to promote tissue ingrowth and vascularization, and yet be free of tissue ingress. Also, the site housing material permits the analyte to pass through the site housing material to the interior cavity to permit measurement by the replaceable analyte sensor. The resealable insertion site provides a for inserting the replaceable analyte sensor into the interior cavity of the site housing material.