MICHAEL J MASTRANGELO
Medical Practice in Meadowbrook, PA
License number
Pennsylvania MD008521E
Category
Medicine
Type
Medical Physician and Surgeon
Address
Address
Meadowbrook, PA 19046
Organization information
See more information about MICHAEL J MASTRANGELO at bizstanding.comMichael J Mastrangelo MD
764 Gln Rd, Meadowbrook, PA 19046
Industry:
Medical Doctor's Office
Medical Doctor, Principal:
Michael Mastrangelo Medical Doctor, Principal, inactive
Professional information
Method Of Inducing An Immune Response Using Vaccinia Virus Recombinants
US Patent:
6475999, Nov 5, 2002
Filed:
Jun 19, 2000
Appl. No.:
09/596716
Inventors:
Michael J. Mastrangelo - Jenkintown PA
Edmund C. Lattime - Princeton NJ
David Berd - Wyncote PA
Laurence C. Eisenlohr - Merion PA
Edmund C. Lattime - Princeton NJ
David Berd - Wyncote PA
Laurence C. Eisenlohr - Merion PA
Assignee:
Thomas Jefferson University - Philadelphia PA
International Classification:
A61K 4800
US Classification:
514 44, 4353201, 435455, 435325
Abstract:
A method of inducing expression of immune active cytokines in tumors in situ is provided wherein a vaccinia virus vector capable of inducing expression of a selected cytokine is generated and injected into a tumor so that cells of the tumor express the selected cytokine. A method of enhancing immunity in a host by administration of a vaccinia virus vector is also provided. Methods of treating cancer by administration of these vaccinia virus vectors are also provided.
Method Of Inducing An Immune Response Using Vaccinia Virus Recombinants
US Patent:
2003008, May 8, 2003
Filed:
Nov 4, 2002
Appl. No.:
10/288663
Inventors:
Michael Mastrangelo - Jenkintown PA, US
Edmund Lattime - Princeton NJ, US
David Berd - Wyncote PA, US
Laurence Eisenlohr - Merion PA, US
Edmund Lattime - Princeton NJ, US
David Berd - Wyncote PA, US
Laurence Eisenlohr - Merion PA, US
International Classification:
A61K048/00, C12N007/00, C12N015/869
US Classification:
424/093200, 514/044000, 435/456000, 435/235100
Abstract:
A method of inducing expression of immune active cytokines in tumors in situ is provided wherein a vaccinia virus vector capable of inducing expression of a selected cytokine is generated and injected into a tumor so that cells of the tumor express the selected cytokine. A method of enhancing immunity in a host by administration of a vaccinia virus vector is also provided. Methods of treating cancer by administration of these vaccinia virus vectors are also provided.
Method Of Inducing An Immune Response Using Vaccinia Virus Recombinants Encoding Gm-Csf
US Patent:
6093700, Jul 25, 2000
Filed:
Feb 20, 1997
Appl. No.:
8/732505
Inventors:
Michael J. Mastrangelo - Jenkintown PA
Edmund C. Lattime - Princeton NJ
David Berd - Wyncote PA
Laurence C. Eisenlohr - Merion PA
Edmund C. Lattime - Princeton NJ
David Berd - Wyncote PA
Laurence C. Eisenlohr - Merion PA
Assignee:
Thomas Jefferson University - Philadelphia PA
International Classification:
A61K 4800, C12N 1500
US Classification:
514 44
Abstract:
A method of inducing expression of immune active cytokines in tumors in situ is provided wherein a vaccinia virus vector capable of inducing expression of a selected cytokine is generated and injected into a tumor so that cells of the tumor express the selected cytokine. A method of enhancing immunity in a host by administration of a vaccinia virus vector is also provided. Methods of treating cancer by administration of these vaccinia virus vectors are also provided.
Method Of Treating Bladder Cancer With Wild Type Vaccinia Virus
US Patent:
6177076, Jan 23, 2001
Filed:
Dec 7, 1998
Appl. No.:
9/206425
Inventors:
Edmund C. Lattime - Princeton NJ
Michael J. Mastrangelo - Jenkintown PA
Michael J. Mastrangelo - Jenkintown PA
Assignee:
Thomas Jefferson University - Philadelphia PA
International Classification:
A01N 6300, A61K 3576
US Classification:
424 936
Abstract:
Methods of treating bladder cancer in a patient by administration of wildtype vaccinia virus are provided.