MICHAEL J BOSSE, MD
Medical Practice at Morehead Medical Dr, Charlotte, NC

2011021, Sep 8, 2011

Jan 13, 2009

12/866939

Kenneth E. Gonsalves - Davidson NC, US
Michael J. Bosse - Charlotte NC, US
John Kent Ellington - Charlotte NC, US
Michael C. Hudson - Charlotte NC, US
James M. Horton - Charlotte NC, US

A61K 38/14, A61K 31/43, A61P 31/04, A61P 19/00, B65D 85/00, B82Y 5/00

514 29, 514 23, 514197, 2064595, 977773, 977906

Compositions that include antimicrobial agents and biodegradable delivery-vehicles adapted to enter a cell and release the antimicrobial agents in the cell as they biodegrade. Also provided are compositions that include first and second delivery vehicles including first and second antimicrobial agents, wherein the first delivery vehicles are adapted to release the first antimicrobial agents at a rate that differs from that at which the second delivery vehicles release the second antimicrobial agents, articles of manufacture that include one or more biodegradable delivery vehicles, and methods of making and using the compositions to treat intracellular and/or extracellular infections are disclosed.

6503217, Jan 7, 2003

Nov 22, 1999

09/447165

Michael A. Gibbs - Charlotte NC
Michael Bosse - Charlotte NC
John Marx - Charlotte NC
Steven Colucciello - Charlotte NC
David Jacobs - Matthews NC
Barbara Ozmar - Charlotte NC

Charlotte-Mecklenburg Hospital Authority - Charlotte NC

A61F 500

602 23, 128869

A pelvic splint for immobilizing and maintaining the annular integrity of the pelvis in the event of a pelvic ring fracture. The pelvic splint extends from about 5-10 cm above the iliac crest down to about the middle third of the thighs and substantially encircles the pelvis of the victim. The splint is then secured about the pelvis of the victim with two or more adjustable straps. The splint comprises a flexible casing having at least one pliable padding layer disposed therein and a plurality of flexible members individually disposed in pockets spaced apart about the casing. Once tightly secured around the pelvis by the adjustable straps, the splint conforms to the contours of the victims pelvic area and stabilizes the pelvis by preventing lateral movement and constraining the pelvis in such a manner to preserve the annular integrity thereof. An associated method of stabilizing a pelvis is also disclosed.

6793639, Sep 21, 2004

Nov 21, 2002

10/300976

Michael A. Gibbs - Charlotte NC
Michael Bosse - Charlotte NC
John Marx - Charlotte NC
Steven Colucciello - Charlotte NC
David Jacobs - Matthews NC
Barbara Ozmar - Charlotte NC

Charlotte-Mecklenburg Hospital Authority - Charlotte NC

A61F 500

602 23, 128869

A pelvic splint for immobilizing and maintaining the annular integrity of the pelvis in the event of a pelvic ring fracture. The pelvic splint extends from about 5-10 cm above the iliac crest down to about the middle third of the thighs and substantially encircles the pelvis of the victim. The splint is then secured about the pelvis of the victim with two or more adjustable straps. The splint comprises a flexible casing having at least one pliable padding layer disposed therein and a plurality of flexible members individually disposed in pockets spaced apart about the casing. Once tightly secured around the pelvis by the adjustable straps, the splint conforms to the contours of the victims pelvic area and stabilizes the pelvis by preventing lateral movement and constraining the pelvis in such a manner to preserve the annular integrity thereof. An associated method of stabilizing a pelvis is also disclosed.

6140285, Oct 31, 2000

Mar 13, 2000

9/524484

David M. Banks - Charlotte NC
Michael J. Bosse - Charlotte NC
Martha H. Meyer - Charlotte NC
Ralph A. Meyer - Charlotte NC
Laura S. Phieffer - Charlotte NC
Kevin L. Smith - Charlotte NC

Charlotte-Mecklenburg Hospital Authority - Charlotte NC

C11D 1700, A61K 750

510130

A composition for cleaning petroleum contaminated surfaces includes 5 to 60 percent by weight of a dioctyl sulfosuccinate salt, 20 to 50 percent by weight of a carrier composition and 10 to 75 percent by weight of a diluent. The preferred carrier composition is a mixture of polyethylene glycol and glycerol. The preferred diluent is water. The preferred concentration of sodium dioctyl sulfosuccinate is about 7% by weight. The preferred dioctyl sulfosuccinate salt is sodium dioctyl sulfosuccinate. A method of cleaning petroleum contaminated surfaces is also provided. The steps include providing a solution containing dioctyl sulfosuccinate salt, a carrier composition, and a diluent as described above and treating the petroleum contaminated surface with the solution in a manner and for a time sufficient to decontaminate the surface. The preferred method of treatment comprises contacting the solution with the petroleum contaminated surface for a time sufficient to create an emulsion and then removing the emulsion. The composition can be used to clean tissue.