DR. MICHAEL GOBLE, PHARM.D.
Pharmacy at Robinson Ave, San Diego, CA
License number
California 61699
Category
Pharmacy
Type
Pharmacist
Address
Address
535 Robinson Ave, San Diego, CA 92103
Phone
(619) 291-3705
Personal information
See more information about MICHAEL GOBLE at radaris.comName
Address
Phone
110 7Th St, Pacific Grove, CA 93950
52450 Eisenhower Dr, La Quinta, CA 92253
3415 Lebon Dr APT 318, San Diego, CA 92122
517 Americano Way, Fairfield, CA 94533
78 S Rosemead Blvd, Pasadena, CA 91107
Professional information
Inhibitors Of Hepatitis C Virus Rna-Dependent Rna Polymerase, And Compositions And Treatments Using The Same
US Patent:
2003019, Oct 16, 2003
Filed:
Mar 31, 2003
Appl. No.:
10/403537
Inventors:
Allen Borchardt - San Diego CA, US
Michael Goble - San Diego CA, US
Michael Goble - San Diego CA, US
Assignee:
Pfizer Inc.
International Classification:
A61K031/427, A61K031/4184, A61K031/366, C07D417/02, C 07D 4 5/02
US Classification:
514/365000, 514/394000, 514/460000, 548/204000, 548/304700, 549/292000
Abstract:
Compounds of formula I are hepatitis C virus (HCV) RNA-dependent RNA polymerase (RdRp) inhibitors, and are useful in therapeutic and prophylactic treatment of persons infected with hepatitis C virus.
Compounds And Methods For Preparing Methanesulfonamides
US Patent:
2004016, Aug 26, 2004
Filed:
Nov 20, 2003
Appl. No.:
10/478594
Inventors:
Sonja Mackey - Galesburg MI, US
Michael Matison - Kalamazoo MI, US
Haifeng Wu - Portage MI, US
Paul Herrinton - Portage MI, US
Michael Goble - San Diego CA, US
Moses McMillian - Portage MI, US
Vikram Kalthod - Mattawan MI, US
Michael Matison - Kalamazoo MI, US
Haifeng Wu - Portage MI, US
Paul Herrinton - Portage MI, US
Michael Goble - San Diego CA, US
Moses McMillian - Portage MI, US
Vikram Kalthod - Mattawan MI, US
International Classification:
C07C311/35
US Classification:
564/086000
Abstract:
A process for preparing (S)-(-)-N-[4-[4-[ethyl(6-fluoro-6-methylheptyl)amino]-1-hydroxy]phenyl]methanesulfonamide hemifumarate salt, which comprises reacting N-[4[(2S)-tetrahydro-5-hydroxy-2-furanyl]phenyl]methanesulfonamide (IIa) with fluoroamine (III) in the presence of triacetoxyborohydride and ethyl acetate to provide [4-[4-[ethyl(6-fluoro-6-metylheptyl)amino]-1-hydroxy]phenyl]methanesulfonamide (I) anll then converting I into the hemifumarate salt Ia. A process for preparing IIa is also claimed as well as intermediates IIa-lId.
Compounds And Methods For Preparing Methanesulfonamides
US Patent:
7232930, Jun 19, 2007
Filed:
Feb 28, 2005
Appl. No.:
11/068287
Inventors:
Sonja Suzanne MacKey - Galesburg MI, US
Michael E. Matison - Kalamazoo MI, US
Haifeng Wu - Portage MI, US
Michael Paul Goble - San Diego CA, US
Moses W. McMillan - Portage MI, US
Vikram Gurudath Kalthod - Mattawan MI, US
Michael E. Matison - Kalamazoo MI, US
Haifeng Wu - Portage MI, US
Michael Paul Goble - San Diego CA, US
Moses W. McMillan - Portage MI, US
Vikram Gurudath Kalthod - Mattawan MI, US
Assignee:
Pharmacia & Upjohn Company - Kalamazoo MI
International Classification:
C07C 303/40, C07C 311/09, C07C 211/15
US Classification:
564 99, 549323, 549475, 560 17, 564510
Abstract:
A process for preparing (S)-(−)-N-[4-[4-[ethyl(6-fluoro-6-methylheptyl)amino]-1-hydroxy]phenyl]methanesulfonamide hemifumarate salt, which comprises reacting N-[4-[(2S)-tetrahydro-5-hydroxy-2-furanyl]phenyl]methanesulfonamide(IIa) with fluoroamine (III) in the presence of triacetoxyborohydride and ethyl acetate to provide [4-[-4-[ethyl(6-fluoro-6-methylheptyl)amino]-1-hydroxylphenyl]methanesulfonamide (I) and then converting I into the hemifumarate salt Ia. A process for preparing IIa is also claimed as well as intermediates IIa-IId.