MICHAEL FOLEY
Plumbers in Boston, MA

License number
Massachusetts 31107
Issued Date
Jan 4, 2008
Expiration Date
May 1, 2018
Type
Journeyman Plumber
Address
Address
Boston, MA 02127

Organization information

See more information about MICHAEL FOLEY at bizstanding.com

Michael Foley MD

736 Cambridge St, Brighton, MA 02135

Industry:
Gastroenterology, Internist
Phone:
(617) 783-4994 (Phone)
Michael Thomas Foley

Professional information

Michael Foley Photo 1

Michael Foley, Brighton MA

Work:
SMG Gastroenterology
11 Nevins St, Brighton, MA 02135 Sehc at Hanscom
1609 Eglin St, Hanscom AFB, MA 01731 Caritas St. Elizabeth's Medical Center
736 Cambridge St, Brighton, MA 02135


Michael Andrew Foley Photo 2

Michael Andrew Foley, Boston MA - Lawyer

Address:
Sawyer & Company Inc
50 Congress St, Boston 02109
(617) 227-7033
Licenses:
New York - Currently registered 1981
Education:
Vermont Law School


Michael Foley Photo 3

Combinations Of Drugs (E.g., A Benzimidazole And Pentamidine) For The Treatment Of Neoplastic Disorders

US Patent:
6693125, Feb 17, 2004
Filed:
Jan 24, 2001
Appl. No.:
09/768870
Inventors:
Alexis Borisy - Boston MA
Curtis Keith - Boston MA
Michael A. Foley - Chestnut Hill MA
Brent R. Stockwell - Boston MA
Assignee:
CombinatoRx Incorporated - Boston MA
International Classification:
A61K 31415
US Classification:
514388, 514631
Abstract:
The invention features a method for treating a patient having a cancer or other neoplasm, by administering to the patient (i) a benzimidazole or a metabolite or analog thereof; and (ii) pentamidine or a metabolite or analog thereof simultaneously or within 14 days of each other in amounts sufficient to inhibit the growth of the neoplasm.


Michael Foley Photo 4

Methods For Identifying Combinations Of Entities As Therapeutics

US Patent:
2006017, Aug 10, 2006
Filed:
Apr 18, 2006
Appl. No.:
11/379179
Inventors:
Brent STOCKWELL - New York NY, US
Alexis BORISY - Arlington MA, US
Michael FOLEY - Chestnut Hill MA, US
International Classification:
C40B 40/02
US Classification:
435007200
Abstract:
The invention features a method of screening two-entity or higher order combinations for biological activity using combinational arrays. The method includes the steps of: (a) providing the entities, (b) creating an array of combinations of entities, (c) providing a test element that includes one or more distinct biological moieties, (d) contacting the array of combinations of entities with the test element under conditions that ensure that each entity/test element contacting is segregated from the others, (e) detecting or measuring a property of the test element, and (f) identifying combinations of entities that cause an effect on the property of the test element that is different from the effect of an entity of the combination by itself.


Michael Foley Photo 5

Combinations Of Drugs For The Treatment Of Neoplasms

US Patent:
2004011, Jun 17, 2004
Filed:
Jul 11, 2003
Appl. No.:
10/617424
Inventors:
Alexis Borisy - Arlington MA, US
Curtis Keith - Boston MA, US
Michael Foley - Chestnut Hill MA, US
Brent Stockwell - Boston MA, US
Debra Gaw - Reading MA, US
M. Nichols - Boston MA, US
Margaret Lee - Middleton MA, US
International Classification:
A61K031/55, A61K031/5415, A61K031/538, A61K031/496
US Classification:
514/217000, 514/225200, 514/229800, 514/253030, 514/297000
Abstract:
The invention features a method for treating a patient having a cancer or other neoplasm by administering to the patient two compounds simultaneously or within 14 days of each other in amounts sufficient to treat the patient.


Michael Foley Photo 6

Cyclopamine Analogues And Methods Of Use Thereof

US Patent:
7230004, Jun 12, 2007
Filed:
Aug 26, 2005
Appl. No.:
11/213534
Inventors:
Julian Adams - Boston MA, US
Alfredo C. Castro - Winchester MA, US
Michael A. Foley - Chestnut Hill MA, US
Somarajan Nair Janardanan Nair - Belmont MA, US
Marta Nevalainen - Quincy MA, US
James R. Porter - Brighton MA, US
Martin R. Tremblay - Melrose MA, US
Assignee:
Infinity Discovery, Inc. - Cambridge MA
International Classification:
A61K 31/438, A61K 31/4355, C07D 491/10, C07D 491/048
US Classification:
514278, 546 18, 546 15
Abstract:
The present invention provides compositions and methods for modulating smoothened-dependent pathway activation. The present invention provides analogs of cyclopamine that can be used to counteract the phenotypic effects of unwanted activation of a hedgehog pathway, such as resulting from hedgehog gain-of-function, Ptc loss-of-function or smoothened gain-of-function mutations. The compounds of the present invention are particularly useful in treating cancers.


Michael Foley Photo 7

Compounds And Compositions For Treating Cancer

US Patent:
8349832, Jan 8, 2013
Filed:
Sep 2, 2010
Appl. No.:
12/874306
Inventors:
Michael Andrew Foley - Chestnut Hill MA, US
Robert Gould - Beverly MA, US
Peter Elliott - Marlboro MA, US
Assignee:
Canthera Therapeutics - Boston MA
The Massachusetts General Hospital Corporation - Boston MA
International Classification:
A61K 31/5377, A61K 31/4412, C07D 413/12, C07D 211/86, A61P 35/00
US Classification:
5142355, 514350, 544131, 546298
Abstract:
The invention relates to compounds and composition for the treatment and prevention of cancer. The invention also covers all diseases that may be treated by selective modulation of levels of reactive oxygen species in diseased cells versus normal cells. Methods for the preparation and administration of such compositions are also disclosed.


Michael Foley Photo 8

Combinations Of Drugs (E.g., A Benzimidazole And Pentamidine) For The Treatment Of Neoplastic Disorders

US Patent:
2004006, Apr 1, 2004
Filed:
Oct 2, 2003
Appl. No.:
10/677664
Inventors:
Alexis Borisy - Arlington VA, US
Curtis Keith - Boston MA, US
Michael Foley - Chestnut Hill MA, US
Brent Stockwell - Boston MA, US
International Classification:
A61K031/4184
US Classification:
514/394000
Abstract:
The invention features a method for treating a patient having a cancer or other neoplasm, by administering to the patient (i) a benzimidazole or a metabolite or analog thereof; and (ii) pentamidine or a metabolite or analog thereof simultaneously or within 14 days of each other in amounts sufficient to inhibit the growth of the neoplasm.


Michael Foley Photo 9

Cyclopamine Analogues And Methods Of Use Thereof

US Patent:
7875628, Jan 25, 2011
Filed:
Jul 10, 2008
Appl. No.:
12/171208
Inventors:
Julian Adams - Boston MA, US
Alfredo C. Castro - Winchester MA, US
Michael A. Foley - Chestnut Hill MA, US
Marta Nevalainen - Quincy MA, US
James R. Porter - Rowley MA, US
Martin R. Tremblay - Melrose MA, US
Assignee:
Infinity Discovery, Inc. - Cambridge MA
International Classification:
A61K 31/4355, C12N 9/99
US Classification:
514302, 514278, 435184
Abstract:
The present invention provides compositions and methods for modulating smoothened-dependent pathway activation. The present invention provides analogs of cyclopamine that can be used to counteract the phenotypic effects of unwanted activation of a hedgehog pathway, such as resulting from hedgehog gain-of-function, Ptc loss-of-function or smoothened gain-of-function mutations. The compounds of the present invention are particularly useful in treating cancers.


Michael Foley Photo 10

Combinations For The Treatment Of Immunoinflammatory Disorders

US Patent:
2011022, Sep 15, 2011
Filed:
Mar 15, 2011
Appl. No.:
13/048587
Inventors:
Curtis Keith - Boston MA, US
Alexis Borisy - Arlington MA, US
Grant Zimmermann - Somerville MA, US
Palaniyandi Manivasakam - West Roxbury MA, US
Nicole W. Hurst - Boston MA, US
Michael A. Foley - Chestnut Hill MA, US
International Classification:
G01N 33/566, C12N 5/078
US Classification:
435 792, 435375
Abstract:
The invention features pharmaceutical compositions that include dipyridamole and a corticosteroid.