Michael E. Kinzie
Engineers at Glenwood Dr, Lafayette, CO

2012008, Apr 12, 2012

Oct 7, 2011

13/269512

Thomas G. DILORENZO - Arvada CO, US
Glen Delbert ANTWILER - Lakewood CO, US
Michael E. KINZIE - Lafayette CO, US
Brian J. Nankervis - Thornton CO, US
Monique Givens - Westminster CO, US
Casey V. Medina - Westminster CO, US
Jon A. Dodd - Littleton CO, US

CARIDIANBCT, INC. - Lakewood CO

C12Q 3/00, C12M 1/36

435 3, 4352865

Embodiments described herein generally relate to methods and systems for using an air removal chamber as a control for a process in a cell expansion system. The air removal chamber may be mounted on a fluid conveyance assembly for use with the system. Fluid is pumped into a fluid containment chamber of the air removal chamber, in which the level of fluid in the fluid containment chamber may be monitored through the use of one or more sensors. The sensors are capable of detecting air, a lack of fluid, fluid, and/or a gas/fluid interface, e.g., an air/fluid interface, at measuring positions within the air removal chamber. Protocols for use with the system may include one or more stop conditions. In an embodiment, the stopping of a process is automated based on the detection of air, a lack of fluid, and/or a gas/fluid interface in the air removal chamber.

2012008, Apr 12, 2012

Oct 7, 2011

13/269351

Glen Delbert ANTWILER - Lakewood CO, US
Patrick J. HOWLEY - Highlands Ranch CO, US
Michael E. KINZIE - Lafayette CO, US
Jon A. DODD - Littleton CO, US
Casey V. Medina - Westminster CO, US

CARIDIANBCT, INC. - Lakewood CO

G06F 3/048

715763

Embodiments described herein generally relate to methods and systems for customizing protocols for use with a cell expansion system. Through a user interface, a user may create a custom task for loading, growing and/or harvesting cells. A custom task may comprise one or more steps, in which a user may add or omit steps, as desired. Data may be entered for settings associated with a custom task, in which embodiments provide for such data to be entered each time the custom task is performed. In another embodiment, the settings for a custom task may be configured, in which such settings may be stored and retrieved upon selection of the custom task. Customization and configuration of a custom task may occur using a diagram view of the cell expansion system, in which process settings are associated with graphical user interface elements.

2014005, Feb 20, 2014

Aug 20, 2013

13/971652

Thomas G. DiLorenzo - Arvada CO, US
Michael E. Kinzie - Lafayette CO, US
Mark E. Jones - Littleton CO, US

Terumo BCT, Inc. - Lakewood CO

C12M 1/00

435393, 435383, 4352931

One or more embodiments are described directed to a method and system for concentrating components of a fluid circulated through a cell growth chamber such as a cell growth chamber. Accordingly, embodiments include methods and systems that utilize a tangential flow filter to concentrate components of a fluid that in embodiments includes expanded cells. In embodiments, a concentrated fluid component and a concentrated cell component are generated by flowing the fluid with expanded cells across a tangential flow filter. The concentrated cell component may be recirculated to the tangential flow filter to reach some desired concentration of cells. The concentrated fluid component may be collected to utilize cellular-produced constituents in the concentrated fluid component.

2012008, Apr 12, 2012

Oct 7, 2011

13/269323

Glen Delbert ANTWILER - Lakewood CO, US
Patrick J. HOWLEY - Highlands Ranch CO, US
Michael E. KINZIE - Lafayette CO, US
Jon A. DODD - Littleton CO, US
Casey V. MEDINA - Westminster CO, US

CARIDIANBCT, INC. - Lakewood CO

G06F 3/048, G06F 3/041, C12M 1/00

345173, 4352891, 715780

Embodiments described herein generally relate to methods and systems for configuring settings of a cell expansion system including a bioreactor. Through a user interface, a user may configure display settings, system settings, and settings associated with protocols for loading, growing and/or harvesting cells. In configuring settings for protocols and associated processes, a diagram view or window of the cell expansion system is displayed in embodiments. The diagram view displays the process settings as graphical user interface elements. Settings available for configuration are enabled for selection in the diagram view. The diagram view allows the user to visualize the settings available for task configuration and to configure enabled settings. Configured settings are stored and capable of retrieval for subsequent execution or modification of the applicable protocol.