Inventors:
Wei Chen - Chapel Hill NC, US
Minyong Chen - Durham NC, US
H. Kim Lyerly - Chapel Hill NC, US
Lawrence S. Barak - Durham NC, US
Robert Mook - Chapel Hill NC, US
Takuya Osada - Chapel Hill NC, US
Michael A. Morse - Raleigh NC, US
International Classification:
A61K 31/167, G01N 33/574, A61P 9/00, C12Q 1/68, A61K 31/277, A61K 31/18
US Classification:
514521, 514622, 514617, 514604, 514619, 435 611, 435 723, 435 71, 435 612, 435 792, 436501
Abstract:
Methods of treating Wnt/Frizzled-related diseases, comprising administering niclosamide compounds are provided. Methods of predicting whether a disease will respond to treatment with a niclosamide compound are also provided.