Inventors:
Lap-Chee Tsui - Toronto, CA
John R. Riordan - Toronto, CA
Francis S. Collins - Ann Arbor MI, US
Johanna M. Rommens - Willowdale, CA
Michael C. Iannuzzi - Ann Arbor MI, US
Bat-Sheva Kerem - Toronto, CA
Mitchell L. Drumm - Ann Arbor MI, US
Manuel Buchwald - Toronto, CA
Assignee:
HSC Research Development Corporation - Toronto
The Board of Regents Acting for and on Behalf of The University of Michigan - Ann Arbor MI
International Classification:
C12P021/06, C07K014/00
US Classification:
435 691, 4352523, 4353201, 435325, 536 231, 530350
Abstract:
The cystic fibrosis gene and its gene product are described for both the normal and mutant forms. The genetic and protein information is used in developing DNA diagnosis, protein diagnosis, carrier and patient screening, drug and gene therapy, cloning of the gene and manufacture of the protein, and development of cystic fibrosis affected animals.