MICHAEL A BONO
Vehicle Board in Collegeville, PA

6230703, May 15, 2001

Jun 2, 1999

9/324275

Michael Bono - Collegeville PA

A61M 1100

12820014

Improved aerosol inhalation devices are provided. The devices include an aerosol source for generating an aerosol; a first conduit, having a proximal end, the first conduit providing passage of the aerosol to the patient; a first chamber at the proximal end of the first conduit, adjacent to the aerosol source; a second conduit providing passage of gaseous medium from the patient; a second chamber; and a first valve disposed between the first chamber and the second chamber. The first valve remains closed during exhalation by the patient and opens at least partially during inhalation. The device also includes a second valve disposed between the second conduit and the second chamber, which remains closed during inhalation by the patient and opens at least partially during exhalation by said patient. The gaseous medium exhaled by the patient can optionally contain material of which the aerosol is formed, such as liquid droplets. The invention also provides methods for making the devices, and for using the devices to deliver therapeutic and diagnostic material in aerosol form to a patient.

5603314, Feb 18, 1997

Mar 22, 1995

8/409190

Michael Bono - Collegeville PA

A61M 1600

12820021

An improved filtration device suitable for reducing exhaled particles in an aerosol inhalation device. The filtration device includes a body portion having an interior chamber which communicates with an inlet and outlet opening through the chamber wall. Within the chamber is a substance recovery media designed to capture a portion of the exhaled particles from the patient and for assisting in returning a portion of the captured particles back to the patient, such as by a nebulizer. The filtration device further includes a filter layer located within the interior chamber for filtering out contaminants, such as viruses and bacteria, in the gaseous medium prior to releasing the remaining portion of the gaseous medium into the environment. Aerosol inhalation devices containing such filters are also provided by this invention.

D433125, Oct 31, 2000

Jun 3, 1999

D/105810

Michael Bono - Collegeville PA

2902

D24110

5630409, May 20, 1997

Mar 22, 1995

8/409360

Michael Bono - Collegeville PA
Gary Ruff - West Chester PA

A61M 1600

12820018

Improved nebulizers and aerosol inhalation devices including these nebulizers are provided by this invention. The disclosed nebulizers are suitable for supplying an aerosol mist to a patient and include a liquid inlet for receiving a liquid, a gas inlet for receiving a pressurized gas and an aerosol outlet for providing an aerosol mist. An important aspect of this invention is the addition of gas swirling means or flow controlling means for creating a swirling action or a tangential velocity to the gas forming the aerosol. The nebulizer and other devices of this invention can produce an aerosol mist having an obscuration of at least 10% and a median droplet size of less than 1. mu. m.

5611332, Mar 18, 1997

Mar 22, 1995

8/409259

Michael Bono - Collegeville PA

A61M 1600

12820018

Improved aerosol inhalation devices including a nebulizer and a rain-off chamber for returning droplets of liquid medication or diagnostics exhaled by the patient back to the nebulizer for reatomization.

D295797, May 17, 1988

Nov 14, 1985

6/805144

Michael Bono - Collegeville PA
Frank J. Rossi - Pottstown PA

Amici, Inc. - Royersford PA

D29 7