METIN KURTOGLU
Physician at Claughton Is Dr, Miami, FL
License number
Florida 15053
Issued Date
May 19, 2010
Effective Date
Jun 26, 2014
Expiration Date
Jun 23, 2014
Category
Health Care
Type
Registration for Resident/HSE Physician
Address
Address
800 Claughton Island Dr #901, Miami, FL 33131
Phone
(305) 761-0155
Personal information
See more information about METIN KURTOGLU at radaris.comName
Address
Phone
2796 Shipping Ave, Miami, FL 33133
2269 15Th St, Miami, FL 33145
2523 36Th Ave, Miami, FL 33133
7713 Kendall Dr, Miami, FL 33156
800 Claughton Island Dr, Miami, FL 33131
Professional information
See more information about METIN KURTOGLU at trustoria.com
Compositions And Methods For Inducing Cancer Cell Death
Compositions And Methods For Inducing Cancer Cell Death
US Patent:
2013018, Jul 18, 2013
Filed:
Aug 15, 2011
Appl. No.:
13/817207
Inventors:
Theodore Lampidis - Miami FL, US
Metin Kurtoglu - Miami Beach FL, US
Metin Kurtoglu - Miami Beach FL, US
Assignee:
UNIVERSITY OF MIAMI - Miami FL
International Classification:
A61K 31/7004, A61K 31/198, A61K 31/713
US Classification:
514 44 A, 514 23
Abstract:
Described herein are pharmaceutical compositions including a sugar or mannose analog (e.g., 2-DG) and an inhibitor of at least one of PERK and GCN2 (e.g., an inhibitor of PERK and an inhibitor of GCN2) for treating cancer, and methods of treating cancer in a subject involving administration of these pharmaceutical compositions. Pharmaceutical compositions [or inducing death of cancer cells include a therapeutically effective amount of a pharmaceutical composition including: a pharmaceutically acceptable carrier, a sugar analog in an amount effective for inhibiting the growth of cancer cells, and an inhibitor of at least one of: PERK and GCN2 in an amount effective for blocking phosphorylation of eif2-1″t in the cancer cells, wherein the combined amounts of the sugar analog and the inhibitor of at least one of: PERK and GCN2 are sufficient for inducing death of the cancer cells.
Mannose Derivatives For Killing Tumor Cells
Mannose Derivatives For Killing Tumor Cells
US Patent:
2009022, Sep 3, 2009
Filed:
Feb 26, 2007
Appl. No.:
12/280541
Inventors:
Theodore J. Lampidis - Miami FL, US
Metin Kurtoglu - Miami FL, US
Jonathan C. Maher - Miami FL, US
Metin Kurtoglu - Miami FL, US
Jonathan C. Maher - Miami FL, US
Assignee:
University of Miami - Miami FL
International Classification:
A61K 31/35, A61P 35/00
US Classification:
514460
Abstract:
A method for treating cancer by killing selected tumor cells such as human breast, non-small cell lung cancer cells, pancreatic cancer cells, osteosarcoma cancer cells, and glioblastoma cells, includes administering to a patient in need of treatment, an effective amount of at least one mannose analog such as 2-DG or 2-FM or 2-CM. The killing is believed to be due to an interference with glycosylation. A theranostic method includes determining whether a patient. cancer tumor sample comprises cells sensitive to killing to at least one mannose analog due to an interference with glycosylation.
Treatment Using Continuous Low Dose Application Of Sugar Analogs
Treatment Using Continuous Low Dose Application Of Sugar Analogs
US Patent:
2011018, Jul 28, 2011
Filed:
May 26, 2009
Appl. No.:
12/994265
Inventors:
Theodore J. Lampidis - Miami FL, US
Metin Kurtoglu - Miami FL, US
Metin Kurtoglu - Miami FL, US
Assignee:
UNIVERSITY OF MIAMI - Miami FL
International Classification:
A61K 31/7004, A61P 35/00
US Classification:
514 23
Abstract:
Methods and uses of low dosage nonmetabolizable D-glucose analogs and mannose analogs such as 2-deoxy-D-glucose, 5-thio-D-glucose, 2-fluoro-2-deoxy-D-glucose, 2-chloro-2-deoxy-D-glucose, 2-bromo-2-deoxy-D-glueose, 2-deoxy-2-fluoro-mannose, 2-deoxy-2-chloro-mannose, 3-deoxy mannose, 4-deoxy mannose, and 2,3 didioxy mannose, for the treatment of tumors.
Mitochondrial Inhibitors And Uses Thereof
Mitochondrial Inhibitors And Uses Thereof
US Patent:
2012007, Mar 22, 2012
Filed:
Sep 21, 2011
Appl. No.:
13/238912
Inventors:
Theodore Lampidis - Miami FL, US
Metin Kurtoglu - Miami Beach FL, US
Metin Kurtoglu - Miami Beach FL, US
Assignee:
UNIVERSITY OF MIAMI - Miami FL
International Classification:
A61K 31/427, A61K 33/36, A61K 38/13, A61K 31/7004, A61K 31/195, A61K 31/19, A61P 35/00, C12Q 1/02, C07C 69/738, C07D 417/12, C07C 57/12, C07C 69/736, C07C 59/68, C07C 233/87, C07D 309/30, C12N 5/071, C07H 3/08, C07C 233/56, C07C 53/16, C12Q 1/34, A61K 31/575
US Classification:
424629, 514182, 514369, 514 205, 514 23, 514563, 514557, 435 29, 560 52, 548183, 554224, 560 62, 562471, 562451, 549292, 435375, 536 111, 562575, 562602, 435 18
Abstract:
Compositions which modulate mitochondrial functions treat diseases associated with cells that are hyperactively using their endoplasmic reticulum. Screening assays identify agents which modulate mitochondrial functions.