Inventors:
Mervyn Maze - San Francisco CA, US
Marc Feldman - London, GB
Niccolo Terrando - San Francisco CA, US
Mario Cibelli - London, GB
Daqing Ma - London, GB
Michael Fertleman - London, GB
Assignee:
IMPERIAL INNOVATIONS LIMITED - London
International Classification:
A61K 39/395
Abstract:
The present invention provides method, uses and agents for preventing or reducing cognitive decline in a patient following a planned inflammatory trigger. Such planned inflammatory trigger can be a surgical procedure or chemotherapy. The invention further provides methods, uses and agents for reducing cognitive decline in a patient with a cognitive disorder, wherein said patient has been exposed to an inflammatory trigger. Pharmaceutical compositions and kits are also provided.