Inventors:
Anthony A. Coniglio - Branchburg NJ
Francis R. Plat - Skillman NJ
Melvin S. Blumenthal - Yardley PA
Assignee:
Bristol-Myers Squibb Co. - Princeton NJ
Sanofi-Synthelabo - Paris
International Classification:
A61K 31675, A61K 3155, A61K 3144, A61K 3141, A61K 31415, A61K 3140
Abstract:
A method is provided for preventing a cerebral infarction by administering to a patient a combination of an ADP-receptor blocking antiplatelet drug, such as clopidogrel, in combination with an antihypertensive agent such as an angiotensin AII antagonist (for example, irbesartan), an ACE inhibitor (for example, fosinopril) or a NEP/ACE inhibitor such as omapatrilat.