Inventors:
Peter Elias - Mill Valley CA, US
Kenneth Feingold - San Rafael CA, US
Matthias Schmuth - San Francisco CA, US
Assignee:
The Regents of the University of California, a California Corporation - Oakland CA
International Classification:
A61K031/426, A61K031/421, A61K009/00
US Classification:
424/400000, 514/365000, 514/374000
Abstract:
Disorders of the skin and mucous membrane that have a disrupted or dysfunctional epidermal barrier, disturbed differentiation, or inflammation are treated or prevented by topical application of compounds that are activators of peroxisome proliferator-activated receptor-delta.