Inventors:
David B. Berkowitz - Lincoln NE, US
Sylvain Broussy - Lincoln NE, US
Argiris Efstratiadis - Athens, GR
Apostolos Klinakis - Marousi, GR
Matthias Szabolcs - New York NY, US
International Classification:
A61K 49/00, C07D 317/70, A61K 31/343, C12N 9/99, C12N 15/74, A01K 67/033, A61P 35/00
US Classification:
800 3, 549432, 514463, 435184, 4353201, 800 13, 800 21, 800 10
Abstract:
Compounds, compositions, methods of making, and methods of using analogues of (−)-picropodophyllin, as well as a transgenic animal model and its use for identifying anticancer agents.