DR. MATTHIAS DOMINIKUS HOFER, MD
Urology at Chicago Ave, Chicago, IL

License number

Illinois 227833

Professional information

See more information about MATTHIAS DOMINIKUS HOFER at trustoria.com

Matthias Dominikus Hofer, Chicago IL

Specialties:

Urologist

Address:

303 E Chicago Ave, Chicago, IL 60611

Dr. Matthias D Hofer, Chicago IL - MD (Doctor of Medicine)

Specialties:

Urology

Address:

251 E Huron St SUITE 3-150, Chicago 60611
(312) 926-2000 (Phone), (312) 926-0239 (Fax)
NORTHWESTERN MEMORIAL HOSPITAL
251 E Huron St, Chicago 60611
(312) 926-6895 (Phone), (312) 926-6374 (Fax)
303 E Chicago Ave, Chicago 60611
(312) 503-3238 (Phone)

Languages:

English

Treatment Of Cancers Characterized By Chromosomal Rearrangement Of The Nut Gene

US Patent:

2011021, Sep 1, 2011

Filed:

Jul 21, 2009

Appl. No.:

13/055381

Inventors:

Christopher French - Boston MA, US
Jon Aster - Lexington MA, US
Matthias Hofer - Chicago IL, US
James Bradner - Cambridge MA, US

Assignee:

THE BRIGHAM AND WOMEN'S HOSPITAL, INC. - Boston MA
DANA-FARBER CANCER INSTITUTE - BOSTON MA

International Classification:

A61K 31/7088, A61K 31/16, A61K 31/395, A61K 31/403, A61K 31/4406, A61P 35/00

US Classification:

514 44 A, 514616, 514431, 514419, 514357

Abstract:

The present invention is directed, inter alia, to methods of treating NUT midline carcinoma (NMC) by administering compounds that promote increased histone acetylation. The invention also includes assay methods for determining the responsiveness of NMC to specific histone deacetylases and other compounds.