Inventors:
Matthew F. KALADY - Cleveland Heights OH, US
Hemant ISHWARAN - Pinecrest FL, US
International Classification:
C40B 30/04, G01N 33/566, C40B 40/06, C12Q 1/68
US Classification:
506 9, 435 612, 435 71, 506 16
Abstract:
Applicants have identified a 36-gene signature that is associated with recurrence of stage I and II rectal cancers not treated with chemotherapy or radiation. This signature can be used to identify early stage rectal cancer patients that may need additional therapy beyond surgery to treat their cancer as well as identify patients that will not benefit from therapy other than surgery.