DR. MASON W DIAMOND, D.D.S.
Dentist at Springfield Ave, Irvington, NJ

2014004, Feb 13, 2014

Sep 23, 2013

14/033979

- , unknown
Satish Pulapura - Bridgewater NJ, US
William Edelman - Sharon MA, US
Arikha Moses - New York NY, US
Mason Diamond - Wayne NJ, US
Shari Timothy - N. Brunswick NJ, US

TYRX, INC. - Monmouth Junction NJ
TYRX PHARMA, INC. - Monmouth Junction NJ

A61L 27/34, A61F 2/00

606151, 4273722, 427314

The present invention relates to medical prostheses and methods of manufacturing those devices. In particular, the prostheses are temporarily stiffened meshes with particular coatings to provide initial stiffness and thereby permit easier surgical handling for treatment or reconstruction of soft tissue defects. Preferred embodiments include surgical meshes coated with one or more biodegradable polymers that can act as a stiffening agent by coating the filaments or fibers of the mesh to temporarily immobilize the contact points of those filaments or fibers and/or by increasing the stiffness of the mesh by at least 1.1 times its original stiffness. The devices of the invention can also provide relief from various post-operative complications associated with their implantation, insertion or surgical use. By including biologically active agents and/or drugs in the coating, the devices provide prophylaxis for and can alleviate side effects or complications associated with the surgery or use of prostheses in general.

2009001, Jan 15, 2009

Nov 6, 2007

11/936049

Fatima Buevich - Highland Park NJ, US
Frank Do - Jersey City NJ, US
William McJames - Bellemeade NJ, US
Satish Pulapura - Bridgewater NJ, US
William Edelman - Sharon MA, US
Arikha Moses - New York NY, US
Mason Diamond - Wayne NJ, US
Shari Timothy - North Brunswick NJ, US

TyRx Pharma, Inc. - Monmouth Junction NJ

A61B 17/08, A61F 2/02

606151, 623 1111

The present invention relates to medical prostheses and methods of manufacturing those devices. In particular, the prostheses are temporarily stiffened meshes with particular coatings to provide initial stiffness and thereby permit easier surgical handling for treatment or reconstruction of soft tissue defects. Preferred embodiments include surgical meshes coated with one or more biodegradable polymers that can act as a stiffening agent by coating the filaments or fibers of the mesh to temporarily immobilize the contact points of those filaments or fibers and/or by increasing the stiffness of the mesh by at least 1.1 times its original stiffness. The devices of the invention can also provide relief from various post-operative complications associated with their implantation, insertion or surgical use. By including biologically active agents and/or drugs in the coating, the devices provide prophylaxis for and can alleviate side effects or complications associated with the surgery or use of prostheses in general.

8636753, Jan 28, 2014

Feb 8, 2007

11/672929

Fatima Buevich - Highland Park NJ, US
Frank Do - Jersey City NJ, US
William McJames - Bellemeade NJ, US
Satish Pulapura - Bridgewater NJ, US
William Edelman - Sharon MA, US
Arikha Moses - NY NY, US
Mason Diamond - Wayne NJ, US
Shari Timothy - Brunswick NJ, US

TYRX, Inc. - Monmouth Junction NJ

A61F 2/02, B05D 1/02

606151, 424426, 427 231, 623 2375

The present invention relates to medical prostheses and methods of manufacturing those devices. In particular, the prostheses are temporarily stiffened meshes with particular coatings to provide initial stiffness and thereby permit easier surgical handling for treatment or reconstruction of soft tissue defects. Preferred embodiments include surgical meshes coated with one or more biodegradable polymers that can act as a stiffening agent by coating the filaments or fibers of the mesh to temporarily immobilize the contact points of those filaments or fibers and/or by increasing the stiffness of the mesh by at least 1. 1 times its original stiffness. The devices of the invention can also provide relief from various post-operative complications associated with their implantation, insertion or surgical use. By including biologically active agents and/or drugs in the coating, the devices provide prophylaxis for and can alleviate side effects or complications associated with the surgery or use of prostheses in general.

8591531, Nov 26, 2013

Nov 6, 2007

11/936054

Fatima Buevich - Highland Park NJ, US
Arikha Moses - New York City NY, US
Frank Do - Jersey City NJ, US
William McJames - Bellemeade NJ, US
William Edelman - Sharon MA, US
Mason Diamond - Wayne NJ, US
Satish Pulapura - Bridgewater NJ, US

TYRX, Inc. - Monmouth Junction NJ

A61B 17/08, B65D 69/00

606151, 206570

Biodegradable polymer-coated surgical meshes formed into pouches are described for use with cardiac rhythm management devices (CRMs) and other implantable medical devices. Such meshes are formed into a receptacle, e. g. , a pouch or other covering, capable of encasing, surrounding and/or holding the cardiac rhythm management device or other implantable medical device for the purpose of securing it in position, inhibiting or reducing bacterial growth, providing pain relief and/or inhibiting scarring or fibrosis on or around the CRM or other implantable medical device. Preferred embodiments include surgical mesh pouches coated with one or more biodegradable polymers that can act as a stiffening agent by coating the filaments or fibers of the mesh to temporarily immobilize the contact points of those filaments or fibers and/or by increasing the stiffness of the mesh by at least 1. 1 times its original stiffness. The pouches of the invention can also provide relief from various post-operative complications associated with their implantation, insertion or surgical use, and, optionally, include one or more drugs in the polymer matrix of the coating to provide prophylactic effects and/or alleviate side effects or complications associated with the surgery or implantation of the CRM or other implantable medical device.

2008012, Jun 5, 2008

Nov 6, 2007

11/936051

Fatima Buevich - Highland Park NJ, US
Frank Do - Jersey City NJ, US
William McJames - Bellemeade NJ, US
William Edelman - Sharon MA, US
Arikha Moses - New York City NY, US
Mason Diamond - Wayne NJ, US

TyRx Pharma, Inc. - Monmouth Junction NJ

A61B 19/02, B65D 69/00, A61K 31/445, A61K 31/496, A61K 31/195, A61P 23/00, A61P 31/00

206572, 424426, 514330, 5142541, 514563

Biodegradable and resorbable polymer pouches are described for use with cardiac rhythm mamagent devices (CRMs) and other implantable medical devices (IMDs), i.e., a pouch, covering, or other receptacle capable of encasing, surrounding and/or holding the CRM or other IMD for the purpose of securing it in position, inhibiting or reducing bacterial growth, providing pain relief and/or inhibiting scarring or fibrosis on or around the CRM or other IMD. Optionally, the biodegradable and resorbable pouches of the invention include one or more drugs in the polymer matrix to provide prophylactic effects and alleviate side effects or complications associated with the surgery or implantation of the CRM or other IMD.