Inventors:
Karl Kavalkovich - Baltimore MD
Raymond Boynton - Watertown MA
Mary Murphy - Baltimore MD
Frank Barry - Baltimore MD
Assignee:
Osiris Therapeutics, Inc. - Baltimore MD
International Classification:
C12N 1110
US Classification:
424 937, 424426, 435178, 435182, 435395
Abstract:
Disclosed are a composition of chemically defined components which support in vitro and in vivo chondrogenesis of mesenchymal stem cells, a method for in vitro and in vivo chondrogenic induction of such stem cells, and a method of forming human chondrocytes in vitro and in vivo from such stem cells.