Inventors:
Donald J. EATON - Los Altos CA, US
Mary Lynn Moran - Woodside CA, US
Rodney A. Brenneman - San Juan Capistrano CA, US
International Classification:
A61M 31/00
Abstract:
The invention provides biodegradable implants for treating sinusitis. The biodegradable implants have a size, shape, density, viscosity, and/or mucoadhesiveness that prevents them from being substantially cleared by the mucociliary lining of the sinuses during the intended treatment period. The biodegradable implants include a sustained release therapeutic, e.g., an antibiotic, a steroidal anti-inflammatory agent, or both. The biodegradable implants may take various forms, such as rods, pellets, beads, strips, or microparticles, and may be delivered into a sinus in various pharmaceutically acceptable carriers.